Optical Detection of Immune Complexes Using Colloidal Gold Nanoparticles
- Авторлар: Spitsyn A.N.1, Utkin D.V.1, Kireev M.N.1, Sharapova N.A.1, Erokhin P.S.1, Germanchuk V.G.1, Kochubey V.I.2,3
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Мекемелер:
- Russian Antiplague Research Institute Microbe
- Chernyshevsky Saratov National Research State University
- National Research Tomsk State University
- Шығарылым: Том 125, № 5 (2018)
- Беттер: 810-814
- Бөлім: Applied Optics
- URL: https://ogarev-online.ru/0030-400X/article/view/165866
- DOI: https://doi.org/10.1134/S0030400X18110280
- ID: 165866
Дәйексөз келтіру
Аннотация
The possibility of detecting the formation of immune complexes with the use of antibodies labeled with colloidal gold nanoparticles and optical spectroscopy is considered. Changes in the spectral characteristics of sols of gold nanoparticles with diameters of 15, 60, and 90 nm conjugated with immunoglobulins in the presence of especially dangerous infectious agents are recorded and analyzed. The data obtained indicate that the developed methodological approach to optical detection of immune complexes may be promising for creating immunochemical methods of identification of infectious agents.
Авторлар туралы
A. Spitsyn
Russian Antiplague Research Institute Microbe
Хат алмасуға жауапты Автор.
Email: rusrapi@microbe.ru
Ресей, Saratov, 410005
D. Utkin
Russian Antiplague Research Institute Microbe
Email: rusrapi@microbe.ru
Ресей, Saratov, 410005
M. Kireev
Russian Antiplague Research Institute Microbe
Email: rusrapi@microbe.ru
Ресей, Saratov, 410005
N. Sharapova
Russian Antiplague Research Institute Microbe
Email: rusrapi@microbe.ru
Ресей, Saratov, 410005
P. Erokhin
Russian Antiplague Research Institute Microbe
Email: rusrapi@microbe.ru
Ресей, Saratov, 410005
V. Germanchuk
Russian Antiplague Research Institute Microbe
Email: rusrapi@microbe.ru
Ресей, Saratov, 410005
V. Kochubey
Chernyshevsky Saratov National Research State University; National Research Tomsk State University
Email: rusrapi@microbe.ru
Ресей, Saratov, 410012; Tomsk, 634050
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