Analysis of Blood Serum by the Method of Refractometry in Antitumor Therapy in Patients with Multiple Myeloma


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Abstract

The serum of patients with multiple myeloma was examined by refractometric methods before and after the course of antitumor therapy. It was found that the amount of protein in the serum of patients with multiple myeloma, determined by the value of the serum refractive index, tended to decrease after the course of treatment. The value of the refractive index of blood serum can be used as an additional criterion for assessing the dynamics of changes in blood-serum properties during antitumor therapy.

About the authors

L. V. Plotnikova

ITMO University

Author for correspondence.
Email: ljusja@mail.ru
Russian Federation, St. Petersburg, 197101

A. M. Polyanichko

St. Petersburg State University

Email: ljusja@mail.ru
Russian Federation, St. Petersburg, 199034

M. O. Kobeleva

ITMO University

Email: ljusja@mail.ru
Russian Federation, St. Petersburg, 197101

A. A. Nikekhin

ITMO University

Email: ljusja@mail.ru
Russian Federation, St. Petersburg, 197101

M. V. Uspenskaya

ITMO University

Email: ljusja@mail.ru
Russian Federation, St. Petersburg, 197101

A. V. Kayava

ITMO University; Centre de Recherche en Biologie Cellulaire de Montpellier, UMR 5237 CNRS; Institut de Biologie Computationnelle (IBC)

Email: ljusja@mail.ru
Russian Federation, St. Petersburg, 197101; Montpellier; Montpellier, 34095

A. D. Garifullin

Russian Scientific Research Institute of Hematology and Transfusiology

Email: ljusja@mail.ru
Russian Federation, St. Petersburg, 191024

S. V. Voloshin

Russian Scientific Research Institute of Hematology and Transfusiology

Email: ljusja@mail.ru
Russian Federation, St. Petersburg, 191024

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