On the possibility of noninvasive polarimetric determination of glucose content in skin

Abstract

Based on real structure and optical properties of the dermis, we analyzed the possibility of polarimetric measurement of glucose content in the skin. It was shown that, at physiological concentrations of glucose in the interstitial fluid, the optical activity of glucose is not manifested in the polarization and optical properties of the tissue, since the optical activity of glucose is almost completely suppressed by the linear birefringence of the dermis.