Long-term luminescence of sensibilizers in tissues at the conditions of oxygen deficiency due to photodynamic effect
- Авторы: Ishemgulov A.T.1, Letuta S.N.1, Pashkevich S.N.1, Alidzhanov E.K.1, Lantukh Y.D.1
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Учреждения:
- Orenburg State University
- Выпуск: Том 123, № 5 (2017)
- Страницы: 828-834
- Раздел: Geometrical and Applied Optics
- URL: https://ogarev-online.ru/0030-400X/article/view/165578
- DOI: https://doi.org/10.1134/S0030400X1711008X
- ID: 165578
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Аннотация
Long-term luminescence of organic dyes (xanthene dyes, halogen substituted fluoroscein) was used for an in vitro study of the photodynamic effect of exogenic probes in malignant tumors and healthy tissues of mice. It is shown that the photodynamic activity of oxygen and the dynamics of its concentration in tissues can be estimated from the delayed fluorescence of exogenic probes caused by singlet–triplet annihilation of singlet oxygen and excited triplet states of the molecules of photosensitizer dyes. It is found that quenching of long-term luminescence of photosensitizers significantly differs in tumors and normal tissues.
Об авторах
A. Ishemgulov
Orenburg State University
Автор, ответственный за переписку.
Email: azamat.ischemgulov@yandex.ru
Россия, Orenburg, 460018
S. Letuta
Orenburg State University
Email: azamat.ischemgulov@yandex.ru
Россия, Orenburg, 460018
S. Pashkevich
Orenburg State University
Email: azamat.ischemgulov@yandex.ru
Россия, Orenburg, 460018
E. Alidzhanov
Orenburg State University
Email: azamat.ischemgulov@yandex.ru
Россия, Orenburg, 460018
Yu. Lantukh
Orenburg State University
Email: azamat.ischemgulov@yandex.ru
Россия, Orenburg, 460018
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