Effect of polypeptides from sea anemone Heteractis crispa on the rodent blood pressure, heart rate, and hemostasis
- Авторы: Skobtsova L.A.1,2, Dyachenko I.A.1,2, Andreev Y.A.3, Logashina Y.A.3, Murashev A.N.1,2, Grishin E.V.3
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Учреждения:
- Pushchino Branch, Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry
- Pushchino State Institute of Natural Sciences
- Shemyakm–Ovchinnikov Institute of Bioorganic Chemistry
- Выпуск: Том 470, № 1 (2016)
- Страницы: 228-230
- Раздел: General Biology
- URL: https://ogarev-online.ru/0012-4966/article/view/153852
- DOI: https://doi.org/10.1134/S0012496616050069
- ID: 153852
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Аннотация
АРНС1–3 peptides, modulators of TRPV1 receptors, have been administered to SD rats to study their influence on the animal hemostatic system, heart rate, and blood pressure. None of АЗРС1–3 polypeptides have any effect on the hemostatic system. Both АРНС1 and АРНС2 polypeptides increased significantly the heart rate, but they did not affect blood pressure, which was probably caused by an ability of these polypeptides to modify animal thermoregulation.
Об авторах
L. Skobtsova
Pushchino Branch, Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry; Pushchino State Institute of Natural Sciences
Email: dyachenko@bibch.ru
Россия, Pushchino, Moscow oblast; Pushchino, Moscow oblast
I. Dyachenko
Pushchino Branch, Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry; Pushchino State Institute of Natural Sciences
Автор, ответственный за переписку.
Email: dyachenko@bibch.ru
Россия, Pushchino, Moscow oblast; Pushchino, Moscow oblast
Ya. Andreev
Shemyakm–Ovchinnikov Institute of Bioorganic Chemistry
Email: dyachenko@bibch.ru
Россия, Moscow
Yu. Logashina
Shemyakm–Ovchinnikov Institute of Bioorganic Chemistry
Email: dyachenko@bibch.ru
Россия, Moscow
A. Murashev
Pushchino Branch, Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry; Pushchino State Institute of Natural Sciences
Email: dyachenko@bibch.ru
Россия, Pushchino, Moscow oblast; Pushchino, Moscow oblast
E. Grishin
Shemyakm–Ovchinnikov Institute of Bioorganic Chemistry
Email: dyachenko@bibch.ru
Россия, Moscow
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