Semax prevents learning and memory inhibition by heavy metals

A. N. Inozemtsev; S. B. Bokieva; O. V. Karpukhina; K. Z. Gumargalieva; A. A. Kamensky; N. F. Myasoedov

doi:10.1134/S0012496616030066

Semax prevents learning and memory inhibition by heavy metals

Autores: Inozemtsev A.N.¹, Bokieva S.B.², Karpukhina O.V.¹^,2, Gumargalieva K.Z.³, Kamensky A.A.¹, Myasoedov N.F.⁴
Afiliações:
1. Moscow State University
2. Khetagurov North Ossetian State University
3. Semenov Institute of Chemical Physics
4. Institute of Molecular Genetics
Edição: Volume 468, Nº 1 (2016)
Páginas: 112-114
Seção: Physiology
URL: https://ogarev-online.ru/0012-4966/article/view/153713
DOI: https://doi.org/10.1134/S0012496616030066
ID: 153713

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Separate and joint effect of Semax, ascorbic acid, lead diacetate, and ammonium molybdate on avoidance conditioning in rats was studied. It was established that the heavy metal salts inhibited the avoidance response, and the peptide counteracted this inhibition as strongly as ascorbic acid or to a comparable degree. These findings confirm the antioxidant properties of Semax.