Email this article Semax prevents learning and memory inhibition by heavy metals
- Authors: Inozemtsev A.N.1, Bokieva S.B.2, Karpukhina O.V.1,2, Gumargalieva K.Z.3, Kamensky A.A.1, Myasoedov N.F.4
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Affiliations:
- Moscow State University
- Khetagurov North Ossetian State University
- Semenov Institute of Chemical Physics
- Institute of Molecular Genetics
- Issue: Vol 468, No 1 (2016)
- Pages: 112-114
- Section: Physiology
- URL: https://ogarev-online.ru/0012-4966/article/view/153713
- DOI: https://doi.org/10.1134/S0012496616030066
- ID: 153713
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Abstract
Separate and joint effect of Semax, ascorbic acid, lead diacetate, and ammonium molybdate on avoidance conditioning in rats was studied. It was established that the heavy metal salts inhibited the avoidance response, and the peptide counteracted this inhibition as strongly as ascorbic acid or to a comparable degree. These findings confirm the antioxidant properties of Semax.
About the authors
A. N. Inozemtsev
Moscow State University
Author for correspondence.
Email: a_inozemtsev@mail.ru
Russian Federation, Moscow, 119992
S. B. Bokieva
Khetagurov North Ossetian State University
Email: a_inozemtsev@mail.ru
Russian Federation, Vladikavkaz, North Ossetia
O. V. Karpukhina
Moscow State University; Khetagurov North Ossetian State University
Email: a_inozemtsev@mail.ru
Russian Federation, Moscow, 119992; Vladikavkaz, North Ossetia
K. Z. Gumargalieva
Semenov Institute of Chemical Physics
Email: a_inozemtsev@mail.ru
Russian Federation, Moscow
A. A. Kamensky
Moscow State University
Email: a_inozemtsev@mail.ru
Russian Federation, Moscow, 119992
N. F. Myasoedov
Institute of Molecular Genetics
Email: a_inozemtsev@mail.ru
Russian Federation, Moscow
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