Atria Depolarization in Rats with Alcoholic Cardiomyopathy

S. L. Smirnova; I. M. Roshchevskaya; M. P. Roshchevsky; I. B. Tsorin; V. N. Stolyaruk; M. B. Vititnova; L. G. Kolik; S. A. Kryzhanovskii

doi:10.1134/S0012496618020035

Atria Depolarization in Rats with Alcoholic Cardiomyopathy

Authors: Smirnova S.L.¹, Roshchevskaya I.M.¹, Roshchevsky M.P.¹, Tsorin I.B.², Stolyaruk V.N.², Vititnova M.B.², Kolik L.G.², Kryzhanovskii S.A.²
Affiliations:
1. Komi Research Center, Ural Branch
2. Zakusov Research Institute of Pharmacology
Issue: Vol 479, No 1 (2018)
Pages: 41-43
Section: Physiology
URL: https://ogarev-online.ru/0012-4966/article/view/154226
DOI: https://doi.org/10.1134/S0012496618020035
ID: 154226

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Abstract

Chronotopography of atrial subepicardium depolarization has been studied in a rat model of alcoholic cardiomyopathy. Formation of independent sources of initial atrial activity has been detected in the right and left atria. These sources induced the formation of several depolarization fronts that propagated autonomously, and this can be regarded as the cause of atrial arrhythmia.