Отправить статью по E-mail Mitochondrial DNA Deletion in Offspring of Female Mice Exposed to X-Rays
- Авторы: Lomaeva M.G.1, Antipova V.N.1, Bezlepkin V.G.1, Gaziev A.I.1
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Учреждения:
- Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences
- Выпуск: Том 64, № 4 (2019)
- Страницы: 528-532
- Раздел: Molecular Biophysics
- URL: https://ogarev-online.ru/0006-3509/article/view/152999
- DOI: https://doi.org/10.1134/S0006350919040109
- ID: 152999
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Аннотация
Abstract—The effects of X-ray exposure on the mitochondrial genome were studied in the offspring of female mice exposed in the preconception period at doses of 0.5 and 2 Gy. Radiation effects were evaluated by the proportion of offspring with a 4974-bp mtDNA deletion. The results showed that irradiation of female mice at these doses did not increase the proportion of offspring with the mtDNA deletion in the brain, spleen, and peripheral blood cells.
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M. Lomaeva
Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences
Автор, ответственный за переписку.
Email: lommg1@gmail.com
Россия, Pushchino, Moscow oblast, 142290
V. Antipova
Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences
Email: lommg1@gmail.com
Россия, Pushchino, Moscow oblast, 142290
V. Bezlepkin
Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences
Email: lommg1@gmail.com
Россия, Pushchino, Moscow oblast, 142290
A. Gaziev
Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences
Email: lommg1@gmail.com
Россия, Pushchino, Moscow oblast, 142290
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