Cell response to extremely weak static magnetic fields
- Авторы: Spivak I.M.1,2,3, Kuranova M.L.1, Mavropulo-Stolyarenko G.R.2, Surma S.V.4, Shchegolev B.F.4,5, Stefanov V.E.2
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Учреждения:
- Institute of Cytology
- St. Petersburg State University
- St. Petersburg Polytechnic University
- Pavlov Institute of Physiology
- Almazov Federal Medical Research Center
- Выпуск: Том 61, № 3 (2016)
- Страницы: 435-439
- Раздел: Cell Biophysics
- URL: https://ogarev-online.ru/0006-3509/article/view/152001
- DOI: https://doi.org/10.1134/S0006350916030180
- ID: 152001
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Аннотация
The effect of an extremely weak static magnetic field (EWSMF) was studied in diploid fibroblast strains that originated from a healthy donor and an ataxia–telangiectasia patient. Indirect immunofluorescence was used to detect p53, p53BP1, and p21. The pattern that occurred in donor cells exposed to EWSMF similar to that observed in DNA damage, viz., the p53 and p21 levels increased and p3BP1 foci formed. No visible change was observed in primary fibroblasts from the ataxia–telangiectasia patient. The results implicate ATM signaling in the fibroblast response to EWSMF.
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Об авторах
I. Spivak
Institute of Cytology; St. Petersburg State University; St. Petersburg Polytechnic University
Email: stefanov@bio.spbu.ru
Россия, Tikhoretskii pr. 4, St. Petersburg, 194064; Universitetskaya nab. 7/9, St. Petersburg, 199034; ul. Politekhnicheskaya 29, St. Petersburg, 195251
M. Kuranova
Institute of Cytology
Email: stefanov@bio.spbu.ru
Россия, Tikhoretskii pr. 4, St. Petersburg, 194064
G. Mavropulo-Stolyarenko
St. Petersburg State University
Email: stefanov@bio.spbu.ru
Россия, Universitetskaya nab. 7/9, St. Petersburg, 199034
S. Surma
Pavlov Institute of Physiology
Email: stefanov@bio.spbu.ru
Россия, nab. Makarova 6, St. Petersburg, 199034
B. Shchegolev
Pavlov Institute of Physiology; Almazov Federal Medical Research Center
Email: stefanov@bio.spbu.ru
Россия, nab. Makarova 6, St. Petersburg, 199034; ul. Akkuratova 2, St. Petersburg, 197341
V. Stefanov
St. Petersburg State University
Автор, ответственный за переписку.
Email: stefanov@bio.spbu.ru
Россия, Universitetskaya nab. 7/9, St. Petersburg, 199034
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