Mathematical Simulation of the Rabbit Heterogeneous Intact Sinoatrial Node Using Similitude Theory

Аннотация

Abstract—In this work, the electrical activity of the heterogeneous intact sinoatrial node at interaction with the atrial myocardium is simulated based on a detailed approach. The reduction of this model used the methods of the theory of similarity. The results of the calculation of the reduced model are compared with the solutions obtained in the initial model. The model also found that an increase in the number of non-excitable sites in the atrial myocardium bordering the pacemaker causes a slowdown in the overall rhythm of electrical activity.