Mechanical properties of films and three-dimensional scaffolds made of fibroin and gelatin


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Abstract

Silk fibroin is a biocompatible and biodegradable material, which can be used in surgery and tissue engineering. To improve the cell adhesion on fibroin surface, gelatin can be added to the items made of fibroin. This work compares the mechanical properties of films and three-dimensional scaffolds made of fibroin and fibroin with gelatin. The addition of 30% gelatin to the fibroin scaffold does not change its microstructure or swelling. The addition of gelatin decreases the mechanical properties of films (decreases the Young’s modulus, the maximum strain and elongation) but increases the shear modulus of the scaffolds.

About the authors

A. Arkhipova

Faculty of Biology

Email: dbagrov@gmail.com
Russian Federation, Moscow, 119234

D. Khaydapova

Department of Soil Physics and Reclamation, Soil Science Faculty

Email: dbagrov@gmail.com
Russian Federation, Moscow, 119234

M. Moisenovich

Faculty of Biology

Email: dbagrov@gmail.com
Russian Federation, Moscow, 119234

K. Shaitan

Faculty of Biology

Email: dbagrov@gmail.com
Russian Federation, Moscow, 119234

D. Bagrov

Faculty of Biology

Author for correspondence.
Email: dbagrov@gmail.com
Russian Federation, Moscow, 119234

V. Zhuikov

Research Center of Biotechnology

Email: dbagrov@gmail.com
Russian Federation, Moscow, 119071

Y. Chudinova

Faculty of Biology; Research Center of Biotechnology

Email: dbagrov@gmail.com
Russian Federation, Moscow, 119234; Moscow, 119071

A. Yarisheva

Chair of High Molecular Weight Compounds, Faculty of Chemistry

Email: dbagrov@gmail.com
Russian Federation, Moscow, 119234

M. Kotlyarova

Faculty of Biology

Email: dbagrov@gmail.com
Russian Federation, Moscow, 119234

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