Отправить статью по E-mail A Multisensory Stripping Voltammetry Method for Analysis of the Generic Anti-Glaucoma Drug Betoptic
- Авторы: Balashova L.M.1,2, Kolesnichenko I.I.3, Namiot V.A.4, Doronin A.N.3, Bakunina N.A.1, Kuznetsova Y.D.1,2, Udaltsov S.N.5
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Учреждения:
- International Scientific and Practical Center for Tissue Proliferation
- Pirogov Russian National Research Medical University
- Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences
- Institute of Nuclear Physics, Moscow State University
- Institute of Physicochemical and Biological Problems in Soil Science, Russian Academy of Sciences
- Выпуск: Том 64, № 6 (2019)
- Страницы: 885-889
- Раздел: Molecular Biophysics
- URL: https://ogarev-online.ru/0006-3509/article/view/153134
- DOI: https://doi.org/10.1134/S0006350919060046
- ID: 153134
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Аннотация
A new electrochemical method for multisensory stripping voltammetry has been used to determine whether it is appropriate for determination of generic forms of the drug Betoptic, that is, Xonef, Betoftan, and Betalink EU in tear fluid. Measurements were carried out on a planar three-electrode interdigitated electrode. It has been shown that this method is effective for determination of the generics. The dynamics of changes in their concentrations over time were examined. After instillation of the generics in glaucoma patients, their concentrations in the lacrimal fluid remained unchanged within 12 h. The list of organic substances that can be determined by the method of multisensory stripping voltammetry has been extended.
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Об авторах
L. Balashova
International Scientific and Practical Center for Tissue Proliferation; Pirogov Russian National Research Medical University
Email: vnamiot@gmail.com
Россия, Moscow, 119034; Moscow, 117997
I. Kolesnichenko
Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences
Email: vnamiot@gmail.com
Россия, Moscow, 119071
V. Namiot
Institute of Nuclear Physics, Moscow State University
Автор, ответственный за переписку.
Email: vnamiot@gmail.com
Россия, Moscow, 119991
A. Doronin
Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences
Email: vnamiot@gmail.com
Россия, Moscow, 119071
N. Bakunina
International Scientific and Practical Center for Tissue Proliferation
Email: vnamiot@gmail.com
Россия, Moscow, 119034
Yu. Kuznetsova
International Scientific and Practical Center for Tissue Proliferation; Pirogov Russian National Research Medical University
Email: vnamiot@gmail.com
Россия, Moscow, 119034; Moscow, 117997
S. Udaltsov
Institute of Physicochemical and Biological Problems in Soil Science, Russian Academy of Sciences
Email: vnamiot@gmail.com
Россия, Pushchino, Moscow oblast, 142290
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