The Role of Erythrocyte Receptors in Regulation of the Conformation and Distribution of Hemoglobin
- Autores: Maksimov G.V.1, Slatinskaya O.V.1, Tkhor E.S.1, Anisimov N.A.2, Mamaeva S.N.3, Shutova V.V.4
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Afiliações:
- Moscow State University
- National Scientific Center Institute of Biomedical Problems
- Ammosov Northeastern Federal University
- Ogarev National Research Mordovia State University
- Edição: Volume 64, Nº 1 (2019)
- Páginas: 57-61
- Seção: Cell Biophysics
- URL: https://ogarev-online.ru/0006-3509/article/view/152847
- DOI: https://doi.org/10.1134/S0006350919010123
- ID: 152847
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Resumo
Abstract—Using Raman spectroscopy, atomic force microscopy, and laser interferometry we found that variations in insulin-like growth factor (IGF-1) and purinergic compounds such as ATP in the blood influence the hemoglobin distribution and hematoporhyrin conformation in hemoglobin in erythrocytes. Our results suggest that receptor activation promotes changes in conformation of cytoskeletal protein molecules and hemoglobin.
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Sobre autores
G. Maksimov
Moscow State University
Autor responsável pela correspondência
Email: gmaksimov@mail.ru
Rússia, Moscow, 119892
O. Slatinskaya
Moscow State University
Email: gmaksimov@mail.ru
Rússia, Moscow, 119892
E. Tkhor
Moscow State University
Email: gmaksimov@mail.ru
Rússia, Moscow, 119892
N. Anisimov
National Scientific Center Institute of Biomedical Problems
Email: gmaksimov@mail.ru
Rússia, Moscow, 123007
S. Mamaeva
Ammosov Northeastern Federal University
Email: gmaksimov@mail.ru
Rússia, Yakutsk, Republic of Sakha (Yakutia), 677000
V. Shutova
Ogarev National Research Mordovia State University
Email: gmaksimov@mail.ru
Rússia, Saransk, Republic of Mordovia, 430005
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