The Role of Erythrocyte Receptors in Regulation of the Conformation and Distribution of Hemoglobin


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Abstract—Using Raman spectroscopy, atomic force microscopy, and laser interferometry we found that variations in insulin-like growth factor (IGF-1) and purinergic compounds such as ATP in the blood influence the hemoglobin distribution and hematoporhyrin conformation in hemoglobin in erythrocytes. Our results suggest that receptor activation promotes changes in conformation of cytoskeletal protein molecules and hemoglobin.

Sobre autores

G. Maksimov

Moscow State University

Autor responsável pela correspondência
Email: gmaksimov@mail.ru
Rússia, Moscow, 119892

O. Slatinskaya

Moscow State University

Email: gmaksimov@mail.ru
Rússia, Moscow, 119892

E. Tkhor

Moscow State University

Email: gmaksimov@mail.ru
Rússia, Moscow, 119892

N. Anisimov

National Scientific Center Institute of Biomedical Problems

Email: gmaksimov@mail.ru
Rússia, Moscow, 123007

S. Mamaeva

Ammosov Northeastern Federal University

Email: gmaksimov@mail.ru
Rússia, Yakutsk, Republic of Sakha (Yakutia), 677000

V. Shutova

Ogarev National Research Mordovia State University

Email: gmaksimov@mail.ru
Rússia, Saransk, Republic of Mordovia, 430005

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