Alterations of Antioxidant and Oxygen Transport Properties of Blood in Adenocarcinoma-Bearing Mice during Chemotherapy
- Авторы: Baizhumanov A.A.1, Elagin V.V.2, Tkhor E.S.1, Parshina E.Y.1, Yusipovich A.I.1, Silicheva M.A.1, Maksimov G.V.1
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Учреждения:
- Department of Biology
- Institute of Biomedical Technologies
- Выпуск: Том 63, № 2 (2018)
- Страницы: 233-236
- Раздел: Complex Systems Biophysics
- URL: https://ogarev-online.ru/0006-3509/article/view/152566
- DOI: https://doi.org/10.1134/S0006350918020045
- ID: 152566
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Аннотация
The influence of murine intestinal adenocarcinoma on the antioxidant status and hemoglobin content in the blood was analyzed. Murine adenocarcinoma was accompanied with a decrease of the nonprotein thiol concentration and an increase in ceruloplasmin. A conformational change in the globin molecule but not in the heme group was revealed in the hemoglobin molecule. The changes in the protein appear to be caused by nonspecific damage that results from the processes of peroxidation.
Об авторах
A. Baizhumanov
Department of Biology
Email: parshinae@gmail.com
Россия, Moscow, 119234
V. Elagin
Institute of Biomedical Technologies
Email: parshinae@gmail.com
Россия, Nizhny Novgorod, 603950
E. Tkhor
Department of Biology
Email: parshinae@gmail.com
Россия, Moscow, 119234
E. Parshina
Department of Biology
Автор, ответственный за переписку.
Email: parshinae@gmail.com
Россия, Moscow, 119234
A. Yusipovich
Department of Biology
Email: parshinae@gmail.com
Россия, Moscow, 119234
M. Silicheva
Department of Biology
Email: parshinae@gmail.com
Россия, Moscow, 119234
G. Maksimov
Department of Biology
Email: parshinae@gmail.com
Россия, Moscow, 119234
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