Mathematical Models of the Kinetics of the Cultivation of Microorganisms

Resumo

Various equations of mathematical models for the kinetics of the development of various biological processes were obtained on the basis of the generalized differential equation of biomass growth. Aerobic periodic cultivation of the yeast Saccharomyces cerevisiae was carried out to provide a comparative evaluation of advantages and disadvantages of four types of mathematical models. It is shown that the exponential model is a particular solution to the generalized differential equation. The developed mathematical model can be used to predict the course of biological processes in time and can serve as a tool for a computational experiment in order to clarify the dependence of the rate of a biological process on changes in certain parameters that affect the development of cells.