The remote effects of radiation after hypofractionated irradiation with protons of Ehrlich ascites carcinoma in mice
- Авторы: Balakin V.E.1, Shemyakov A.E.1, Zaichkina S.I.2, Rozanova O.M.2, Smirnova E.N.2, Romanchenko S.P.2, Sorokina S.S.2, Strelnikova N.S.1
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Учреждения:
- Physical Technical Center, Lebedev Physical Institute
- Institute of Theoretical and Experimental Biophysics
- Выпуск: Том 62, № 1 (2017)
- Страницы: 138-142
- Раздел: Biophysics of Complex Systems
- URL: https://ogarev-online.ru/0006-3509/article/view/152236
- DOI: https://doi.org/10.1134/S0006350917010043
- ID: 152236
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Аннотация
This work focuses on the study of remote effects (duration of remission, recurrence rate, and average lifespan) in mice with Ehrlich ascites carcinoma exposed to oligofractionated irradiation with a pencil scanning beam of protons depending on the volume of the tissue being irradiated and the interval between dose fractions. The results show higher antitumor efficacy and a considerable increase in the average life span of mice after hypofractionated irradiation with a pencil scanning beam of protons at a total dose of 60 Gy of the gross tumor volume compared with the planning target volume.
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Об авторах
V. Balakin
Physical Technical Center, Lebedev Physical Institute
Email: szaichkina@yandex.ru
Россия, Protvino, Moscow Region, 142280
A. Shemyakov
Physical Technical Center, Lebedev Physical Institute
Email: szaichkina@yandex.ru
Россия, Protvino, Moscow Region, 142280
S. Zaichkina
Institute of Theoretical and Experimental Biophysics
Автор, ответственный за переписку.
Email: szaichkina@yandex.ru
Россия, Pushchino, Moscow Region, 142290
O. Rozanova
Institute of Theoretical and Experimental Biophysics
Email: szaichkina@yandex.ru
Россия, Pushchino, Moscow Region, 142290
E. Smirnova
Institute of Theoretical and Experimental Biophysics
Email: szaichkina@yandex.ru
Россия, Pushchino, Moscow Region, 142290
S. Romanchenko
Institute of Theoretical and Experimental Biophysics
Email: szaichkina@yandex.ru
Россия, Pushchino, Moscow Region, 142290
S. Sorokina
Institute of Theoretical and Experimental Biophysics
Email: szaichkina@yandex.ru
Россия, Pushchino, Moscow Region, 142290
N. Strelnikova
Physical Technical Center, Lebedev Physical Institute
Email: szaichkina@yandex.ru
Россия, Protvino, Moscow Region, 142280
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