The nephroprotective effects of taurine in acute kidney injury due to rhabdomyolysis


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Abstract

We studied the effect of taurine on renal function and the prooxidant–antioxidant balance in the kidneys and blood of rats under experimental rhabdomyolysis. It was found that taurine at a dose of 100 mg/kg of animal body weight improves renal function and normalizes prooxidant–antioxidant balance indicators, reducing the intensity of lipid and protein peroxidation and increasing catalase and glutathione peroxidase activities.

About the authors

I. I. Zamorskii

Bukovinian State Medical University

Author for correspondence.
Email: zamorskii@mail.ru
Ukraine, Teatral’naya pl. 2, Chernovtsy, 58002

V. M. Drachuk

Bukovinian State Medical University

Email: zamorskii@mail.ru
Ukraine, Teatral’naya pl. 2, Chernovtsy, 58002

O. M. Goroshko

Bukovinian State Medical University

Email: zamorskii@mail.ru
Ukraine, Teatral’naya pl. 2, Chernovtsy, 58002

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