Measurement of the Temperature Field in a Brain Phantom with Simulated Glioblastoma in Transcranial High-Frequency Hyperthermia

Resumo

This paper presents the results of temperature shift measurements in a brain phantom based on agar gel and including elements simulating a tumor (glioblastoma) and cerebrospinal fluid for assessment of the safety of real courses of high-frequency hyperthermia using a Celsius TCS system. No “hot spots” formed at the boundary between normal brain tissue and fluid and the temperature did not excess physiological values. Higher tempera-tures were produced in the model viable tumor (glioblastoma), reaching the values required for hyperthermic radiosensitization.