Experimental Study of the Binary System Mg 3 (PO 4 ) 2 –Mg 4 Na(PO 4 ) 3

I. I. Preobrazhenskiy; Преображенский И. И.; Ya. Yu. Filippov; Филиппов Я. Ю.; P. V. Evdokimov; Евдокимов П. В.; V. I. Putlyaev; Путляев В. И.

doi:10.31857/S0002337X23050147

Experimental Study of the Binary System Mg₃(PO₄)₂–Mg₄Na(PO₄)₃

作者: Preobrazhenskiy I.I.¹, Filippov Y.Y.¹^,2, Evdokimov P.V.¹^,3^,4, Putlyaev V.I.¹^,3
隶属关系:
1. Faculty of Materials Science, Moscow State University
2. Research Institute of Mechanics, Moscow State University
3. Faculty of Chemistry, Moscow State University
4. Kurnakov Institute of General and Inorganic Chemistry, Russian Academy of Sciences
期: 卷 59, 编号 5 (2023)
页面: 521-528
栏目: Articles
URL: https://ogarev-online.ru/0002-337X/article/view/140161
DOI: https://doi.org/10.31857/S0002337X23050147
EDN: https://elibrary.ru/KCKARG
ID: 140161

如何引用文章

全文:

开放存取

##reader.subscriptionAccessGranted##
受限制的访问

订阅存取

详细
作者简介
参考
补充文件
统计

详细

The Mg3(PO4)2–Mg4Na(PO4)3 system has been studied using thermal analysis, X-ray diffraction, and X-ray microanalysis. Firing the constituent phosphates at 800°C has been shown to cause no phase changes, whereas firing above 1000°C leads to the formation of a single-phase material, which is due to the incongruent melting of the magnesium sodium double orthophosphate Mg4Na(PO4)3. The homogeneity range of the compounds in the Mg3(PO4)2–Mg4Na(PO4)3 system differing in composition has been determined by X-ray microanalysis. The microstructure of Mg3–xNa2x(PO4)2-based ceramic materials prepared by sintering at a temperature of 1000°C has an average grain size under 10 μm. The synthesized bioceramic materials are potentially attractive for use as implants for bone tissue regeneration.

关键词

magnesium phosphates, phase diagram, bioceramics, regenerative medicine

参考

Сафронова Т.В. Неорганические материалы для регенеративной медицины // Неорган. материалы. 2021. Т. 57. № 5. С. 467–499. https://doi.org/10.31857/S0002337X21050067
Фадеева И.В., Фомин А.С., Баринов С.М., Давыдова Г.А., Селезнева И.И., Преображенский И.И., Русаков М.К., Фомина А.А., Волченкова В.А. Синтез и свойства марганецсодержащих кальцийфосфатных материалов // Неорган. материалы. 2020. Т. 56. № 7. С. 738–745. https://doi.org/10.31857/S0002337X20070052
Wang X., Zhai D., Yao X., Wang Y., Ma H., Yu X., Du L., Lin H., Wu C. 3D Printing of Pink Bioceramic Scaffolds for Bone Tumor Tissue Therapy // Appl. Mater. Today. 2022. V. 27. P. 101443. https://doi.org/10.1016/j.apmt.2022.101443
Голованова О.А. Формирование гранул фосфаты кальция/хитозан // Неорган. материалы. 2021. Т. 57. № 9. С. 999–1007. https://doi.org/10.31857/S0002337X21090098
Preobrazhenskiy I.I., Tikhonov A.A., Evdokimov P.V., Shibaev A.V., Putlyaev V.I. DLP Printing of Hydrogel/Calcium Phosphate Composites for the Treatment of Bone Defects // Open Ceram. 2021. V. 6. P. 100115. https://doi.org/10.1016/j.oceram.2021.100115
Солоненко А.П., Блесман А.И., Полонянкин Д.А., Горбунов В.А. Синтез композитов на основе фосфатов и силикатов кальция // Журн. неорган. химии. 2018. Т. 63. № 8. С. 953–960. https://doi.org/10.1134/S0044457X18080214
Преображенский И.И., Тихонов А.А., Климашина Е.С., Евдокимов П.В., Путляев В.И. Набухание акрилатных гидрогелей, наполненных брушитом и октакальциевым фосфатом // Изв. АН. Сер. хим. 2020. № 8. С. 1601–1603. https://elibrary.ru/item.asp?id=43862779
Преображенский И.И., Путляев В.И. Трехмерная печать биосовместимых материалов на основе гидрогелей // Журн. прикл. химии. 2022. Т. 95. № 6. С. 685–699. https://doi.org/10.31857/S0044461822060020
Sun H., Zhang C., Zhang B., Song P., Xu X., Gui X., Chen X., Lu G., Li X., Liang J., Sun J., Jiang Q., Zhou C., Fan Y., Zhou X., Zhang X. 3D Printed Calcium Phosphate Scaffolds with Controlled Release of Osteogenic Drugs for Bone Regeneration // Chem. Eng. J. 2022. V. 427. P. 130961. https://doi.org/10.1016/j.cej.2021.130961
Fadeeva I.V., Goldberg M.A., Preobrazhensky I.I., Mamin G.V., Davidova G.A., Agafonova N.V., Fosca M., Russo F., Barinov S.M., Cavalu S., Rau J.V. Improved Cytocompatibility and Antibacterial Properties of Zinc-Substituted Brushite Bone Cement Based on β-Tricalcium Phosphate // J. Mater. Sci.: Mater. Med. 2021. V. 32. № 9. P. 1–12. https://doi.org/10.1007/s10856-021-06575-x
Zhang S., Zhang X., Zhao C., Li J., Song Y., Xie C., Tao H., Zhang Y., He Y., Jiang Y., Bian Y. Research on an Mg–Zn Alloy as a Degradable Biomaterial // Acta Biomater. 2010. V. 6. № 2. P. 626–640. https://doi.org/10.1016/j.actbio.2009.06.028
Salimi M.H., Heughebaert J.C., Nancollas G.H. Crystal Growth of Calcium Phosphates in the Presence of Magnesium Ions // Langmuir. 1985. V. 1. № 1. P. 119–122. https://doi.org/10.1021/la00061a019
Liu M., Liu H., Feng F., Xie A., Kang G.J., Zhao Y., Hou C.R., Zhou X., DudleyJr S.C. Magnesium Deficiency Causes a Reversible, Metabolic, Diastolic Cardiomyopathy // J. Am. Heart Assoc. 2021. P. e020205. https://doi.org/10.1161/JAHA.120.020205
Gronowicz G., McCarthy M.B. Response of Human Osteoblasts to Implant Materials: Integrin-Mediated Adhesion // J. Orthop. Res. 1996. V. 14. № 6. P. 878–887. https://doi.org/10.1002/jor.1100140606
Zhao X., Yang Z., Liu Q., Yang P., Wang P., Wei S., Liu A., Zhao Z. Potential Load-Bearing Bone Substitution Material: Carbon-Fiber-Reinforced Magnesium-Doped Hydroxyapatite Composites with Excellent Mechanical Performance and Tailored Biological Properties // ACS Biomater. Eng. 2022. https://doi.org/10.1021/acsbiomaterials.1c01247
Chau C., Qiao F., Li Z. Potentiometric Study of the Formation of Magnesium Potassium Phosphate Hexahydrate // J. Mater. Civil Eng. 2012. V. 24. № 5. P. 586–591. https://doi.org/10.1061/(ASCE)MT.1943-5533.0000410
Ewald A., Helmschrott K., Knebl G., Mehrban N., Grover L.M., Gbureck U. Effect of Cold-Setting Calcium- and Magnesium Phosphate Matrices on Protein Expression in Osteoblastic Cells // J. Biomed. Mater. Res. Part B: Appl. Biomater. 2011. V. 96. № 2. P. 326–332. https://doi.org/10.1002/jbm.b.31771
Никитина Ю.О., Петракова Н.В., Ашмарин А.А., Титов Д.Д., Шевцов С.В., Пенкина Т.Н., Кувшинова Е.А., Баринов С.М., Комлев В.С., Сергеева Н.С. Получение и исследование свойств порошков и керамики медьзамещенного гидроксиапатита // Неорган. материалы. 2019. Т. 55. № 10. С. 1123–1129. https://doi.org/10.1134/S0002337X19100117
Преображенский И.И., Путляев В.И. Синтез и фазовые превращения соединений системы Mg4Na(PO4)3–Mg3(PO4)2 в качестве перспективных фаз для изготовления биокерамики // Неорган. материалы. 2022. Т. 58. № 4. С. 367–373. https://doi.org/10.31857/S0002337X22030125
Abbona F., Madsen H.L., Boistelle R. Crystallization of Two Magnesium Phosphates, Struvite and Newberyite: Effect of pH and Concentration // J. Cryst. Growth. 1982. V. 57. № 1. P. 6–14. https://doi.org/10.1016/0022-0248(82)90242-1
PDF-4+ 2010 (Database). Newtown Square: International Centre for Diffraction Data, 2010. http://www.icdd.com/products/pdf2.htm
Majling J., Hanic F. Phase Coexistence in the System Mg3(PO4)2–Ca3(PO4)2–Na3PO4 // Chem. Zv. 1976. V. 30. № 2. P. 145–152.
Kushkevych I., Abdulina D., Dordević D., Rozehnalová M., Vítězová M., Černý M., Svoboda P., Rittmann M.R. Basic Bioelement Contents in Anaerobic Intestinal Sulfate-Reducing Bacteria // Appl. Sci. 2021. V. 11. № 3. P. 1152. https://doi.org/10.3390/app11031152
Martínez-Moreno D., Jiménez G., Chocarro-Wrona C., Carrillo E., Montañez E., Galocha-León C., Clares-Naveros B., Gálvez-Martín P., Rus G., de Vicente J., Marchal J.A. Pore Geometry Influences Growth and Cell Adhesion of Infrapatellar Mesenchymal Stem Cells in Biofabricated 3D Thermoplastic Scaffolds Useful for Cartilage Tissue Engineering // Mater. Sci. Eng., C. 2021. V. 122. P. 111933. https://doi.org/10.1016/j.msec.2021.111933