电邮这篇文章 
发表评论 剖宫产后分离ESKAPE组病原体子宫内膜异位症的内科治疗的预后和有效性
- 作者: Korobkov N.A.1, Bakulina N.V.1, Kakhiani E.I.1
-
隶属关系:
- North-Western State Medical University named after I.I. Mechnikov
- 期: 卷 12, 编号 3 (2020)
- 页面: 35-40
- 栏目: Original research
- URL: https://ogarev-online.ru/vszgmu/article/view/34916
- DOI: https://doi.org/10.17816/mechnikov34916
- ID: 34916
如何引用文章
开放存取
##reader.subscriptionAccessGranted##
订阅存取
详细
目的是确定剖宫产后子宫内膜炎中耐药性ESKAPE病原体（rESKAPE）分离的频率，评估疾病的预后以及分离多药耐药性病原体的初步经验性抗菌治疗的结果。
方法。对圣彼得堡剖宫产后子宫内膜炎的所有病例进行回顾性分析。学习期间：2008年9月-
2019年9月
主要结果。剖宫产术后子宫内膜炎255例，其中68例（26.7％）是由rESKAPE组的病原体引起的。
患有由rESKAPE病原体引起的子宫内膜炎的产妇中，开具初始经验性抗菌药物治疗的临床失败率要高于其他病因的子宫内膜炎（p = 0.0012）；感染过程的严重过程，具有其泛化和子宫切除术的威胁（p < 0.05）。
结论。由rESKAPE-病原体引起的腹部分娩后的内膜炎，与不利的疾病预测和抗微生物治疗不起作用的高风险有关。
作者简介
Nikolay Korobkov
North-Western State Medical University named after I.I. Mechnikov
编辑信件的主要联系方式.
Email: nikolai_korobkov@mail.ru
ORCID iD: 0000-0001-7279-2535
доцент кафедры акушерства и гинекологии
俄罗斯联邦, Saint PetersburgN. Bakulina
North-Western State Medical University named after I.I. Mechnikov
Email: nv_bakulina@mail.ru
ORCID iD: 0000-0003-4075-4096
SPIN 代码: 9503-8950
Scopus 作者 ID: 7201739080
Researcher ID: N-7299-2014
http://www.researcherid.com/rid/N-7299-2014
д.м.н., проф., зав. каф. терапии и клинической фармакологии
俄罗斯联邦, Saint-PetersburgEkaterina Kakhiani
North-Western State Medical University named after I.I. Mechnikov
Email: dr.ekaterina@mail.ru
д.м.н., профессор, декан педиатрического факультета, зав. кафедрой акушерства и гинекологии имени С.Н. Давыдова
俄罗斯联邦, Saint Petersburg参考
- De Socio GV, Rubbioni P, Botta D, et al. Measurement and prediction of antimicrobial resistance in bloodstream infections by ESKAPE and Escherichia coli pathogens. J Glob Antimicrob Resist. 2019;19:154-160. https://doi.org/10.1016/j.jgar.2019.05.013.
- Mulani MS, Kamble EE, Kumkar SN, et al. Emerging strategies to combat ESKAPE pathogens in the era of antimicrobial resistance: A review. Front Microbiol. 2019;10:539-545. https://doi.org/10.3389/fmicb.2019.00539.
- Santajit S, Indrawattana N. Mechanisms of antimicrobial resistance in ESKAPE pathogens. Biomed Res Int. 2016;2016: 2475067. https://doi.org/10.1155/2016/2475067.
- Sandiumenge A, Lisboa T, Gomez F, et al. Effect of antibiotic diversity on ventilator-associated pneumonia caused by ESKAPE organisms. Chest. 2011;140(3):643-651. https://doi.org/10.1378/chest.11-0462.
- Sandiumenge A, Rello J. Ventilator-associated pneumonia caused by ESKAPE organisms: Cause, clinical features, and management. Curr Opin Pulm Med. 2012;18(3):187-193. https://doi.org/10.1097/MCP.0b013 e328351f974.
- Chaintarli K, Lenglet A, Beauzile BD, et al. High prevalence of ESBL-positive bacteria in an obstetrics emergency hospital and neonatal care unit — Haiti, 2016. Infect Control Hosp Epidemiol. 2018;39(11):1381-1383. https://doi.org/10.1017/ice.2018.213.
- Udo EE, Al-Sweih N. Dominance of community-associated methicillin-resistant Staphylococcus aureus clones in a maternity hospital. PloS One. 2017;12(6):e0179563. https://doi.org/10.1371/journal.pone.0179563.
- Rodríguez-Bano J, Navarro MD, Romero L, et al. Clinical and molecular epidemiology of extended-spectrum β-lactamase — producing Escherichia coli as a cause of nosocomial infection or colonization: Implications for control. Clinical Infectious Diseases. 2006;42(1):37-45. https://doi.org/10.1086/498519.
- Rodríguez-Bano J, Navarro MD, Romero L, et al. Epidemiology and clinical features of infections caused by extended-spectrum beta-lactamase-producing Escherichia coli in nonhospitalized patients. J Clin Microbiol. 2004;42(3):1089-1094. https://doi.org/10.1128/JCM.42.3. 1089-1094.2004.
- Kramarov SO, Yevtushenko VV. Carbapenems in clinical practice. Actual Infectology. 2019;7(2):57-62. https://doi.org/10.22141/2312-413x.7.2.2019.161149.
补充文件
