脉冲振荡测量法和计算机断层扫描对先天性脊柱侧凸患儿呼吸系统的评估（初步结果）

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详细

论证。椎体侧表面分割异常和肋骨融合是脊柱和胸部先天性病理中最严重的变异之一，导致胸廓功能不全综合征的发展，表现为胸部无法提供正常的呼吸力学。

本研究的目的介绍先天性胸椎侧凸伴椎体侧表面分割异常和单侧肋骨融合患者的肺功能和X线（CT形态测量）研究的初步结果。

材料与方法。研究设计是一个小的临床系列。该前瞻性研究包括脉冲振荡仪和CT形态测量数据，并对10名3至7岁的胸椎先天性脊柱侧弯并伴有单侧椎体侧表面分割异常和单侧肋骨融合的患者进行多螺旋计算机断层扫描数据的三维重建。

结果。在脉搏振荡测量呼吸功能的研究中，7例临床病例未发现呼吸功能障碍。在3例通气障碍患儿中，根据脉搏振荡测定，最显著的变化是总呼吸阻抗参数，以及谐振频率和电阻分量的频率依赖性。在所有患者中，三维肺模型识别的形态测量肺评估指标与脉冲振荡测量肺功能的研究结果相一致。

结论。对先天性脊柱侧凸患儿呼吸功能评估问题的进一步研究在诊断和确定手术治疗的有效性方面似乎都有希望。

作者简介

Sergei V. Vissarionov

H. Turner National Medical Research Center for Children’s Orthopedics and Trauma Surgery

Email: vissarionovs@gmail.com
ORCID iD: 0000-0003-4235-5048
SPIN 代码: 7125-4930
Scopus 作者 ID: 6504128319
Researcher ID: P-8596-2015

MD, PhD, D.Sc., Professor, Corresponding Member of RAS

俄罗斯联邦, Saint Petersburg

Marat S. Asadulaev

H. Turner National Medical Research Center for Children’s Orthopedics and Trauma Surgery

编辑信件的主要联系方式.
Email: marat.asadulaev@yandex.ru
ORCID iD: 0000-0002-1768-2402
SPIN 代码: 3336-8996
Scopus 作者 ID: 57191618743

MD, PhD student

俄罗斯联邦, Saint Petersburg

Elena A. Orlova

Children’s municipal multi-specialty clinical center of high medical technology named after K.A. Rauhfus

Email: eaorlova65@mail.ru
ORCID iD: 0000-0002-3128-980X

MD, PhD, Cand. Sci. (Med.), doctor of functional diagnostics

俄罗斯联邦, Saint Petersburg

Vachtang G. Toriya

H. Turner National Medical Research Center for Children’s Orthopedics and Trauma Surgery

Email: vakdiss@yandex.ru
ORCID iD: 0000-0002-2056-9726
SPIN 代码: 1797-5031

MD, neurosurgeon

俄罗斯联邦, Saint Petersburg

Kirill A. Kartavenko

H. Turner National Medical Research Center for Children’s Orthopedics and Trauma Surgery

Email: med-kart@yandex.ru
ORCID iD: 0000-0002-6112-3309
SPIN 代码: 5341-4492
Scopus 作者 ID: 57193272063

MD, PhD, Cand. Sci. (Med.)

俄罗斯联邦, Saint-Petersburg

Timofey S. Rybinskikh

H. Turner National Medical Research Center for Children’s Orthopedics and Trauma Surgery

Email: timofey1999r@gmail.com
ORCID iD: 0000-0002-4180-5353
SPIN 代码: 7739-4321

6th year student

俄罗斯联邦, Saint Petersburg

Tatyana V. Murashko

H. Turner National Medical Research Center for Сhildren’s Orthopedics and Trauma Surgery

Email: popova332@mail.ru
ORCID iD: 0000-0002-0596-3741
SPIN 代码: 9295-6453

MD, radiologist

俄罗斯联邦, Saint Petersburg

Mikhail A. Khardikov

H. Turner National Medical Research Center for Сhildren’s Orthopedics and Trauma Surgery

Email: denica1990@bk.ru
ORCID iD: 0000-0002-8269-0900
SPIN 代码: 3378-7685
Scopus 作者 ID: 57203014683

MD, PhD, Cand. Sci. (Med.)

俄罗斯联邦, Saint Petersburg

Dmitry N. Kokushin

H. Turner National Medical Research Center for Сhildren’s Orthopedics and Trauma Surgery

Email: partgerm@yandex.ru
ORCID iD: 0000-0002-2510-7213
SPIN 代码: 9071-4853
Scopus 作者 ID: 57193257768

MD, PhD, Cand. Sci. (Med.)

俄罗斯联邦, Saint Petersburg

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补充文件

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2. 图 1 S.患者，5岁。脊柱和胸腔器官在目标结构模式下的多螺旋计算机断层扫描。在多面斜冠状重建（a）和三维图像——最大强度投影（b）。表层阴影图像——前视图（c），后视图（d）椎体外侧表面的异常分割，左侧肋骨融合不全 （后外侧切面）；利用组织分割技术对骨骼和肺实质进行隔离可视化的胸腔重建（e）

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3. 图 2 通过构建基于吸入式多螺旋计算机断层扫描数据的支气管肺系统虚拟三维模型，计算出A.患者（5岁）的肺组织体积。虚拟肺部模型：a——前视图；b——侧视图；c——后视图

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版权所有 © Vissarionov S., Asadulaev M., Orlova E., Toriya V., Kartavenko K., Rybinskikh T., Murashko T., Khardikov M., Kokushin D., 2022

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