Immune status of the workers of technogenic-excited environment manufacture and of population living in this territory

I V Oradovskaya; Орадовская И В; N A Leyko; Лейко Н А; B V Feoktistov; Феоктистов Б В; M A Oprishchenko; Оприщенко М А; L V Luss; Лусс Л В; M F Nikonova; Никонова М Ф; V V Ivanov; Иванов В В; V M Zabelov; Забелов В М; I V Oradovsraya; Oradovsraya I V; LA Leyko; Leyko LA; VV MA Eeoktistov; Eeoktistov VV MA; L V Luss; Luss L V; M F Nikonova; Nikonova M F; V V Ivanov; Ivanov V V; V M Zabelov; Zabelov V M

doi:10.36691/RJA1031

Immune status of the workers of technogenic-excited environment manufacture and of population living in this territory

作者: Oradovskaya IV¹, Leyko NA¹, Feoktistov BV¹, Oprishchenko MA¹, Luss LV¹, Nikonova MF¹, Ivanov VV¹, Zabelov VM¹, Oradovsraya IV¹, Leyko L.¹, Eeoktistov V.M.¹, Luss LV¹, Nikonova MF¹, Ivanov VV¹, Zabelov VM¹
隶属关系:
1. ФБГУ ГНЦ «Институт иммунологии ФМБА России»
期: 卷 6, 编号 5 (2009)
页面: 18-28
栏目: Articles
URL: https://ogarev-online.ru/raj/article/view/121280
DOI: https://doi.org/10.36691/RJA1031
ID: 121280

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Background. To study the influence of technogenic-excited environment manufacture on clinical and immune
parameters of employees and population living in the territory of its influence.
Methods. The analysis of frequency of clinical features of immune dysfunction with clinical, immunolological
and allergological examination was carried out. 689 persons were examined: 474 - the personnel of industrial
complex, 215 - the population which is not working at industrial complex.
Results. Clinical signs of immune dysfunction during 2 year follow-up period were established in 77,3% of
population group. The immune parameters in all groups during 2 year follow-up period in comparison with
those during 1 year follow-up period showed the decreasing of number of leukocytes, T-lymphocytes, CD4+
T-lymphocytes as well as immunoregulative index. It was defined dissociation in level of NK-cells, expressed in
decreasing of absolute values of CD16+ lymphocytes and increasing of their percentage and increasing of CD8+
T-lymphocytes, B-lymphocytes and phagocytosis parameters.

关键词

immune status, personnel, environment, population, risk factors

参考

Орадовская И.В., Оприщенко М.А., Лейко ИА. и соавт. Клинико-иммунологическая и аллергологическая характеристика жителей Среднего Урала. Радиобиология. Радиоэкология, 2000, т. 40, № 2, с. 177-187.
Петров Р.В., Орадовская И.В. Методология, организация и итоги массовых иммунологических обследований. Материалы Всесоюзн. конф. г. Ангарск. 1987, с. 215-234.
Петров Р.В., Хаитов Р.М., Пинегин Б.В. и соавт. Оценка иммунного статуса человека при массовых обследованиях. Методические рекомендации для научных сотрудников и врачей практического здравоохранения. Иммунология. 1992, № 6, с. 51- 62.

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Immune status of the workers of technogenic-excited environment manufacture and of population living in this territory

全文:

详细

关键词

作者简介

I Oradovskaya

N Leyko

B Feoktistov

M Oprishchenko

L Luss

M Nikonova

V Ivanov

V Zabelov

I Oradovsraya

LA Leyko

VV Eeoktistov

L Luss

M Nikonova

V Ivanov

V Zabelov

参考

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