THE MORPHOFUNCTIONAL STATE OF THE ORGANS OF IMMUNE SYSTEM AND LYMPHOCYTE SUBSETS IN THE PERIPHERAL BLOOD OF FEMALE WISTAR RATS IN DIFFERENT PHASES OF THE ESTROUS CYCLE

封面

如何引用文章

全文:

详细

Differences in the morphofunctional state of the immune system of female Wistar rats in different phases of the estrous cycle are revealed. In the phase of diestrus the indices of cortex volume fraction of thymus and volume fraction of white pulp and marginal zone of lymphoid follicles of spleen are higher; the indices of subcapsular layer width of thymus and index of stimulation of granulocytes in the peripheral blood are lower as compared with the phase of proestrus. Differences in the absolute count and the percentage of T and B lymphocytes, T helpers, cytotoxic, activated and regulatory T cells in the peripheral blood of female rats in the phases of proestrus and diestrus aren’t revealed.

参考

  1. Автандилов Г.Г. Медицинская морфометрия / Г.Г. Автандилов. - М.: Медицина, 1990. - 384 с.
  2. Angele M.K. Gender and sex hormones influence the response to trauma and sepsis: potential therapeutic approaches / M.K. Angele, M.C. Frantz, I.H. Chaudry // Clinics. - 2006. - Vol. 61, №5. -P. 479-488.
  3. Changes in the blood thymus barrier of adult rats after estradiol treatment / A. Martin [et al.] // Immunobiol. - 1995. - Vol. 192. - P. 231-248.
  4. Chiang K. Estrogen, neutrophils and oxidation / K. Chiang, S. Parthasarathy, N. Santanam // Life Sci. - 2004. - Vol. 75, №20. - P. 2425-2438.
  5. Different immune responses to abdominal surgery in men and women / M.W. Wichmann [et al.] // Langenbecks Arch. Surg. - 2003. - Vol. 387. - P. 397-401.
  6. Differential effects of male and female gonadal hormones on the intrathymic T cell maturation / B. Pejcic-Karapetrovic [et al.] // Dev. Immunol. - 2001. - Vol. 8. - P. 305-317.
  7. Evaluation of steroid hormone receptor pro tein expression in intact cells using flow cytometry / C.L. Butts [et al.] // Nucl. Recept. Signal. - 2007. - Vol. 5. - P. 7.
  8. Fluctuation of peripheral blood T, B, and NK cells during a menstrual cycle of normal healthy women / S. Lee [et al.] // J. Immunol. - 2010. - Vol. 185. -P. 756-762.
  9. IFN-gamma-inducing transcription factor, T-bet is upregulated by estrogen in murine splenocytes: role of IL-27 but not IL-12 / E. Karpuzoglu [et al.] // Mol. Immunol. - 2007. - Vol. 44, №7. -P 1819-1825.
  10. Российский медико-биологический вестник имени академика И.П. Павлова, №2, 2014 г.
  11. Klein S.L. Sex Hormones and Immunity to Infection / S.L. Klein, C.W. Roberts. -Heidelberg (Germany): Springer-Verlag Berlin Heidelberg, 2010. - P. 1-319.
  12. Low-dose estrogen therapy ameliorates experimental autoimmune encephalomyelitis in two different inbred mouse strains / B.F. Bebo [et al.] // J. Immunol. - 2001. - Vol. 166, № 3. - P. 2080-2089.
  13. Modulation of 17beta-estradiol on the number and cytotoxicity of NK cells in vivo related to MCM and activating receptors / S. Hao [et al.] // Int. Immunopharmacol. - 2007. - Vol. 15. -P. 1765-1775.
  14. Progesterone inhibits glucocorticoid-induced murine thymocyte apoptosis / R.W. McMurray [et al.] // Int. J. Immunopharmacol. - 2000. - Vol. 22, № 11. - P. 955-965.
  15. Suppression of murine allogeneic cell interactions by sex hormones / C. Pavia [et al.] // J. Reprod. Immunol. - 1979. -Vol. l, № l. - P. 33-38.
  16. The effect of estrogens on superoxide anion generation by human neutrophil granulocytes: possible consequences of the antioxidant defense / G. Bekesi [et al.] // Gynecol. Endocrinol. - 2007. -Vol. 2. - P. 1-4.

补充文件

附件文件
动作
1. JATS XML
下载

版权所有 © Simonova E.Y., Kosyreva A.M., 2014

Creative Commons License
此作品已接受知识共享署名 4.0国际许可协议的许可
 


Согласие на обработку персональных данных

 

Используя сайт https://journals.rcsi.science, я (далее – «Пользователь» или «Субъект персональных данных») даю согласие на обработку персональных данных на этом сайте (текст Согласия) и на обработку персональных данных с помощью сервиса «Яндекс.Метрика» (текст Согласия).