Neuroregulatory peptides in medicine
- Authors: Seifulla R.D.1,2, Belous M.V.1,2, Kim E.K.1,2
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Affiliations:
- Central Research Institute for Medical and Biological Problems of Sport
- Central Research Institute of Neurology
- Issue: Vol 70, No 3 (1989)
- Pages: 207-213
- Section: Articles
- URL: https://ogarev-online.ru/kazanmedj/article/view/99891
- DOI: https://doi.org/10.17816/kazmj99891
- ID: 99891
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Abstract
The wide spectrum of pharmacological activity, diversity of biological action, efficiency in low concentrations, absence of accumulation in the body, and low toxicity determine the prospects for the use of peptide bioregulators in clinical practice. At the same time, the existing obstacles in their use in practical medicine are caused by the rapid decomposition after administration, the modulatory character of their action, which depends on the initial functional state of the body, a weakly pronounced effect when taken orally, and the difficulty of crossing the blood-brain barrier. One approach to solving these problems is the targeted synthesis of new highly effective substances with selective and prolonged action, possessing the necessary stability and specific means to receptors along with natural peptides.
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##article.viewOnOriginalSite##About the authors
R. D. Seifulla
Central Research Institute for Medical and Biological Problems of Sport; Central Research Institute of Neurology
Author for correspondence.
Email: info@eco-vector.com
Russian Federation, Moscow; Moscow
M. V. Belous
Central Research Institute for Medical and Biological Problems of Sport; Central Research Institute of Neurology
Email: info@eco-vector.com
Russian Federation, Moscow; Moscow
E. K. Kim
Central Research Institute for Medical and Biological Problems of Sport; Central Research Institute of Neurology
Email: info@eco-vector.com
Russian Federation, Moscow; Moscow
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