Allergic rhinitis as a manifestation of the "atopic phenotype"

Abstract

96 patients with allergic rhinitis aged from 24 to 40 years were under our supervision at the Republican Center of Clinical Immunology. Patients (40 men and 56 women) were followed regularly for 5 years. The duration of the disease did not exceed 10 years. The diagnostic program aimed to establish the signs of "atopic phenotype" and specific hypersensitivity in patients with allergic rhinitis. It included an allergic history, skin testing, provocative nasal tests, test of inhibition of natural emigration of leukocytes (TTEL) with histamine, determination of the number of eosinophils in peripheral blood, assessment of humoral and cellular immunity, HLÂ-typing.

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