Hormonal function of ovaries under pregnancy developing after ECF

With the use of immunoferment method the level of estradiol and progesterone in 78 women with single and 39 women with double pregnancy developing after extracorporal fertilization (ECF) was examined. In case of normal single pregnancy after ECF estradiol and progesterone content corresponds to the indices of control group during the whole period of gestation. Under single pregnancy complicated by threat of abortion low estradiol and progesterone level indicates insufficiency of the yellow body and placenta. Predominance of estrogenic influence turns out to be the decisive factor of late abortion and preterm delivery in pregnant women of this group. Under the threat of abortion in the 1^st term of double pregnancy progesterone level is certain to decrease. The results of the study give proof of the necessity of individual approach to the therapy of abortion threat in cases of single and double pregnancy after ECF.