Email this article Cytokine production by peripheral blood lymphocytes in patients with ovarian epithelial tumors
- Authors: Pavlov R.V.1, Aksenenko V.A.1, Krivoruchko A.Y.1, Pavlenko N.A.1
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Affiliations:
- Stavropol State Medical Academy
- Issue: Vol 50, No 1 (2001)
- Pages: 37-40
- Section: Scientific activity
- URL: https://ogarev-online.ru/jowd/article/view/89004
- DOI: https://doi.org/10.17816/JOWD89004
- ID: 89004
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Abstract
In presence of autoserum, production of IL1b, IL2, IL4, IL6 and TNFa by peripheral blood lymphocytes of 30 patients with epithelial tumors of ovaries and 50 patients with epithelial ovarian cancer of I-IV stages was investigated. The data received enable to ascertain the increase of mononuclear activity during ovarian tumor progression, increase of T-helpers of the second type activity, along with the reduction of T-helpers of the first type activity in peripheral blood of patients, and abnormalities of IL6-dependent mechanism of control of ILIb and TNFa production by peripheral blood lymphocytes of patients with ovarian cancer.
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##article.viewOnOriginalSite##About the authors
R. V. Pavlov
Stavropol State Medical Academy
Email: info@eco-vector.com
Russian Federation
V. A. Aksenenko
Stavropol State Medical Academy
Email: info@eco-vector.com
Russian Federation
A. Yu. Krivoruchko
Stavropol State Medical Academy
Email: info@eco-vector.com
Russian Federation
N. A. Pavlenko
Stavropol State Medical Academy
Author for correspondence.
Email: info@eco-vector.com
Russian Federation
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