Donors of nitric oxide in the treatment of preeclampsia: influence on the state of the endothelium and hemodynamics in the functional mother-placenta-fetus system
- Authors: Malakhovskaya E.A.1, Zainulina M.S.1
 - 
							Affiliations: 
							
- State Medical University named after acad. I.P. Pavlova
 
 - Issue: Vol 53, No 4 (2004)
 - Pages: 42-45
 - Section: Original study articles
 - URL: https://ogarev-online.ru/jowd/article/view/88641
 - DOI: https://doi.org/10.17816/JOWD88641
 - ID: 88641
 
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Abstract
We investigated influence of nitrovasodilators on functional status of endothelium in preeclampsia with measuring of thrombomodulin, sICAM-1 and sVCAM-1 plasma levels. Changes in feto-placental and uteroplacental hemodynamics were analysed after treatment with isosorbide mononitrate and isosorbide dinitrate. Our results showed efficacy of nitric oxide donors in complex therapy of preeclampsia.
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##article.viewOnOriginalSite##About the authors
Elena A. Malakhovskaya
State Medical University named after acad. I.P. Pavlova
							Author for correspondence.
							Email: info@eco-vector.com
				                					                																			                								
candidate of medical sciences, obstetrician-gynecologist
Russian Federation, Saint-PetersburgMarina S. Zainulina
State Medical University named after acad. I.P. Pavlova
														Email: info@eco-vector.com
				                					                																			                								
Doctor of Medical Sciences, Professor, Doctor
Russian Federation, Saint-PetersburgReferences
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