Osteoporosis Prevalence in Women in the Urals Rural Area
- Authors: Kondakova V.G.1, Zakroyeva A.G.2, Zverev S.I.3
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Affiliations:
- Nevyansk Central District Hospital
- Ural State Medical University
- Irbit Central Hospital
- Issue: Vol 29, No 1 (2025)
- Pages: 5-16
- Section: Original study article
- URL: https://ogarev-online.ru/RFD/article/view/292748
- DOI: https://doi.org/10.17816/RFD636984
- EDN: https://elibrary.ru/CRDBTL
- ID: 292748
Cite item
Abstract
BACKGROUND: The rural population of the Russian Federation is underrepresented in osteoporosis studies.
AIM: The aim of the study was to evaluate the prevalence of osteoporosis in rural women of the Urals aged ≥ 50 years.
METHODS: A cluster comprehensive observational study was conducted in 2240 residents of a rural settlement in the Urals. Osteoporosis rates were based on fracture data obtained using a FRAX algorithm and dual-energy X-ray absorptiometry (DXA).
RESULTS: A history of fragility fractures was reported in 15% of the study subjects. An additional 4.4% of patients were diagnosed with osteoporosis using DXA. When other clinical data and FRAX scores were analyzed in subjects who declined DXA, the osteoporosis rates in the study population reached 21.2% and showed an increase with age.
CONCLUSION: The prevalence of osteoporosis in rural women aged ≥ 50 years was 21.2%, and osteoporosis rates increased with age, reaching 38.7% in subjects aged ≥ 85 years. FRAX has been shown to be effective in identifying women at intermediate and high risk of fracture in rural areas, in combination with diagnostic and therapeutic intervention thresholds specific to Russia. Low awareness of osteoporosis in patients with fragility fractures requires a coordinated primary care approach, including osteoporosis education programs for rural populations. Clinical decision making for osteoporosis therapy in 11% of rural women was based on a highly specific intervention threshold calculated using FRAX without consideration of DXA data.
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##article.viewOnOriginalSite##About the authors
Vera G. Kondakova
Nevyansk Central District Hospital
Author for correspondence.
Email: KondakovaGP@gmail.com
ORCID iD: 0000-0001-7272-7311
SPIN-code: 8710-8403
MD
Russian Federation, Nevyansk, Sverdlovsk RegionAlla G. Zakroyeva
Ural State Medical University
Email: zakroeva.alla@mail.ru
ORCID iD: 0000-0003-4839-4427
SPIN-code: 8248-6920
MD, Dr. Sci. (Medicine)
Russian Federation, EkaterinburgSvyatoslav I. Zverev
Irbit Central Hospital
Email: zverevsv@live.ru
ORCID iD: 0009-0007-5120-0263
SPIN-code: 3299-4259
MD
Russian Federation, Irbit, Sverdlovsk RegionReferences
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