Мақаланы E-mail арқылы жіберу In vitro and in vivo biodegradation of silk fabric scaffolds
- Авторлар: Agapov I.I.1, Podbolotova E.I.1,2, Nemets E.A.1, Kirsanova L.A.1, Grudinin N.V.1, Pashutin A.R.1,2, Agapova O.I.1, Efimov A.E.1, Basok Y.B.1, Lyundup A.V.3, Gautier S.V.1,4
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Мекемелер:
- Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Ministry of Health of the Russian Federation
- Moscow Institute of Physics and Technology
- Рeoples’ Friendship University of Russia
- Sechenov University
- Шығарылым: Том 520, № 1 (2025)
- Беттер: 45-49
- Бөлім: Articles
- URL: https://ogarev-online.ru/2686-7389/article/view/287112
- DOI: https://doi.org/10.31857/S2686738925010089
- EDN: https://elibrary.ru/tcqqzj
- ID: 287112
Дәйексөз келтіру
Ашық рұқсат
Рұқсат берілді
Аннотация
This study investigates the biodegradation of natural silk scaffolds made from gauze and satin fabrics under in vitro and in vivo conditions. Experiments were conducted using phosphate-buffered saline and Fenton’s reagent to model degradation. The samples demonstrated high stability under physiological conditions’ model and exhibited varying degradation rates under oxidative stress. In vivo studies on rats revealed good biocompatibility of the scaffolds and a gradual reduction in inflammatory responses. These findings highlight the potential of silk scaffolds for use in various areas of regenerative medicine.
Негізгі сөздер
Толық мәтін
Авторлар туралы
I. Agapov
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Ministry of Health of the Russian Federation
Хат алмасуға жауапты Автор.
Email: igor.agapov@gmail.com
Ресей, Moscow
E. Podbolotova
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Ministry of Health of the Russian Federation; Moscow Institute of Physics and Technology
Email: igor.agapov@gmail.com
Ресей, Moscow; Dolgoprudny
E. Nemets
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Ministry of Health of the Russian Federation
Email: igor.agapov@gmail.com
Ресей, Moscow
L. Kirsanova
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Ministry of Health of the Russian Federation
Email: igor.agapov@gmail.com
Ресей, Moscow
N. Grudinin
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Ministry of Health of the Russian Federation
Email: igor.agapov@gmail.com
Ресей, Moscow
A. Pashutin
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Ministry of Health of the Russian Federation; Moscow Institute of Physics and Technology
Email: igor.agapov@gmail.com
Ресей, Moscow; Dolgoprudny
O. Agapova
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Ministry of Health of the Russian Federation
Email: igor.agapov@gmail.com
Ресей, Moscow
A. Efimov
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Ministry of Health of the Russian Federation
Email: igor.agapov@gmail.com
Ресей, Moscow
Yu. Basok
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Ministry of Health of the Russian Federation
Email: igor.agapov@gmail.com
Ресей, Moscow
A. Lyundup
Рeoples’ Friendship University of Russia
Email: igor.agapov@gmail.com
Ресей, Moscow
S. Gautier
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Ministry of Health of the Russian Federation; Sechenov University
Email: igor.agapov@gmail.com
Academician of the RAS
Ресей, Moscow; MoscowӘдебиет тізімі
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