Evaluation of the antibacterial activity of polyalkenate cement modified with metal-containing nanoparticles
- Authors: Rumyantsev V.A.1, Andreev A.A.1, Frolov G.A.2, Leontieva A.V.1
-
Affiliations:
- Tver State Medical University
- Moscow Institute of Steel and Alloys
- Issue: Vol 25, No 2 (2025)
- Pages: 52-55
- Section: DENTISTRY
- URL: https://ogarev-online.ru/2410-3764/article/view/310108
- DOI: https://doi.org/10.35693/AVP678195
- ID: 310108
Cite item
Full Text
Abstract
Aim – assessment of the level of antibacterial effect of polyalkenate (glass ionomer) cement modified with nanoparticles of vanadium oxide (V2O5), aluminum oxide (Al2O3) and magnetite (Fe3O4) in relation to a test culture of Staphylococcus aureus and a mixed microbiota of saliva.
Material and methods. Colloidal aqueous solutions of metals and their oxides with a stabilizer were obtained using the electroerosion method. The polyalkenate cement “Cemion” was saturated with colloidal solutions during mixing. The antimicrobial activity of the modified filling material was evaluated in relation to the mixed microbiota (saliva) and the test culture of S. aureus by the in vitro disco diffusion method.
Results. The exposure time of the seals was 24 hours at 37 °C in the thermostat. As a result, samples 1-5 showed no areas of delayed microbial growth. Sample 6 showed a growth retardation zone: 19 mm on a cup with S. aureus and 15 mm on a cup with mixed microbiota.
Conclusion. Polyalkenate cement modified with a colloidal aqueous solution of magnetite can be effective in preventing recurrent dental caries.
Keywords
Full Text
##article.viewOnOriginalSite##About the authors
Vitalii A. Rumyantsev
Tver State Medical University
Email: rumyancev_v@tvgmu.ru
ORCID iD: 0000-0001-6045-3333
MD, Dr. Sci. (Medicine), Professor, Head of the Department of Periodontology
Russian Federation, TverAleksei A. Andreev
Tver State Medical University
Author for correspondence.
Email: aandreev01@yandex.ru
MD, Dr. Sci. (Medicine), Professor, Head of the Department of Periodontology
Russian Federation, TverGeorgii A. Frolov
Moscow Institute of Steel and Alloys
Email: georgifroloff@yandex.ru
Cand. Sci. (Chemistry), Associate Professor of the Department of Physical Chemistry
Russian Federation, MoscowAureliya V. Leontieva
Tver State Medical University
Email: aurika171900@mail.ru
Assistant at the Department of Microbiology and Virology with a course in Immunology
Russian Federation, TverReferences
- Bessudnova AR, Rumyantsev VA, Frolov GA, et al. Experimental evaluation of the galvanophoretic dentin nanoimpregnation for recurrent caries prevention. Aspirantskiy vestnik Povolzhiya. 2023;23(2):13-18. [Бессуднова А.Р., Румянцев В.А., Фролов Г.А., Блинова А.В., Битюков В.В. Экспериментальная оценка возможности профилактики рецидивирующего кариеса зубов методом гальванофоретической наноимпрегнации дентина. Аспирантский вестник Поволжья. 2023;23(2):13-18]. doi: 10.55531/2072-2354.2023.23.2.13-18
- Tong HJ, Seremidi K, Stratigaki E, et al. Deep dentine caries management of immature permanent posterior teeth with vital pulp: A systematic review and meta-analysis. J Dent. 2022;1 24:104214. doi: 10.1016/j.jdent.2022.104214
- Márquez-Pérez K, Zúñiga-López CM, Torres-Rosas R, Argueta-Figueroa L. Reported prevalence of dental caries in Mexican children and teenagers. Rev Med Inst Mex Seguro Soc. 2023;61(5):653-660. doi: 10.5281/zenodo.8316465
- Morales-Valenzuela AA, Scougall-Vilchis RJ, Lara-Carrillo E, et al. Enhancement of fluoride release in glass ionomer cements modified with titanium dioxide nanoparticles. Medicine (Baltimore). 2022;101(44):e31434. doi: 10.1097/MD.0000000000031434
- Fierascu RC. Incorporation of nanomaterials in glass ionomer cements-recent developments and future perspectives: A narrative review. Nanomaterials (Basel). 2022;12(21):3827. doi: 10.3390/nano12213827
- Saad Bin Qasim S, Bmuajdad A. The effect of mesoporous silica doped with silver nanoparticles on glass ionomer cements; physiochemical, mechanical and ion release analysis. BMC Oral Health. 2024;24(1):1269. doi: 10.1186/s12903-024-05056-1
- Ramić B, Cvjetićanin M, Bajkin B, et al. Physical and mechanical properties assessment of glass ionomer cements modified with TiO(2) and Mg-doped hydroxyapatite nanoparticles. J Appl Biomater Funct Mater. 2024;22:22808000241282184. doi: 10.1177/22808000241282184
- Tsolianos I, Nikolaidis AK, Koulaouzidou EA, Achilias DS. An Evaluation of Experimental Calcium Ion-Leachable Nanocomposite Glass Ionomer Cements. Nanomaterials (Basel). 2023;13(19):2690. doi: 10.3390/nano13192690
- Rumyantsev VA, Frolov GA, Abdukodirov A, et al. Study of the bactericidal activity of modified dental polyalkenate cements nanoparticles of metals and their compounds. Tver Medical Journal. 2024;5:253-259. (In Russ.). [Румянцев В.А., Фролов Г.А., Абдукодиров А., и др. Изучение бактерицидной активности стоматологических полиалкенатных цементов, модифицированных наночастицами металлов и их соединений. Тверской медицинский журнал. 2024;5:253-259].
- Rumyantceva V, Koshel E, Vinogradov V, et al. Biocide-conjugated magnetite nanoparticles as an advanced platform for biofilm treatment. Therapeutic delivery. 2019;10(4):241-250. doi: 10.4155/tde-2019-0011
Supplementary files
