Evaluation of plant-based UV filters potential in modern concept view of skin photoprotection

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Abstract

A therapeutic plants potential is based on the pharmacological effects due to their phytochemical profile. Today, scientific interest in botanicals is increasing as a result of recent research that looks at the prospect of using these raw materials for the cosmetic industry as a means to protect the skin from the harmful effects of UV rays.

The aim of the study was to evaluate a potential of plant-based UV-filters in modern concept view of skin photoprotection.

Materials and methods. A systematic literature search was carried out using the electronic information arrays PubMed, Scopus, Google Scholar, eLibrary. The search depth was 10 years (the period from 2010 to 2021). The search was carried out by the following keywords: antioxidants, cosmetics, photoprotection, chemical composition, pharmacological action.

Results. In the paper, modern principles of skin photoprotection based on the use of chemical or physical UV-filters are considered and scientifically substantiated A trend for the use of plant-based materials and their components in the formulation of photoprotectors was notified. That is associated with a wide activity spectrum, the absence of a xenobiotic effect, and a high bioavailability of organic plant compounds.

Conclusion. The data analysis from scientific publications demonstrated a potential photoprotective activity of plant-based biologically active substances due to antioxidant, anti-inflammatory and anti-radical effects. The results of the study are a theoretical basis for a further comprehensive experimental study of plant objects in order to obtain a pool of evidence in the field of photoprotection in in vivo experiments.

About the authors

Oksana D. Nemyatykh

Saint-Petersburg State Chemical and Pharmaceutical University

Author for correspondence.
Email: oksana.nemyatyh@pharminnotech.com
ORCID iD: 0000-0001-5933-2120

Doctor of Sciences (Pharmacy), Associate Professor, Professor of Management and Economics Department of Pharmacy, Saint-Petersburg State Chemical and Pharmaceutical University

Russian Federation, 14, Prof. Popov Str., Saint-Petersburg, 197376

Inna I. Terninko

Saint-Petersburg State Chemical and Pharmaceutical University; Testing Laboratory (Medicines Quality Control Center) of Saint-Petersburg State Chemical and Pharmaceutical University

Email: inna.terninko@pharminnotech.com
ORCID iD: 0000-0002-2942-1015

Doctor of Sciences (Pharmacy), Associate Professor, Head of the Structural Subdivision, Testing Laboratory (Medicines Quality Control Center) of Saint-Petersburg State Chemical and Pharmaceutical University

Russian Federation, 14, Prof. Popov Str., Saint-Petersburg, 197376; Bld. A, 14, Prof. Popov Str., Saint-Petersburg, 197376

Askhat S. Sabitov

Asfendiyarov Kazakh National Medical University

Email: acxam78@gmail.com
ORCID iD: 0000-0001-8101-2123

teacher of the School ofPharmacy, Asfendiyarov Kazakh National Medical University, Republic of Kazakhstan

Kazakhstan, Bld. 4, 88, Tole Bi Str., Almaty, 050000

Anastasia I. Lyashko

Saint-Petersburg State Chemical and Pharmaceutical University

Email: anastasia.fitisova@pharminnotech.com
ORCID iD: 0000-0001-9534-0398

Candidate of Sciences (Pharmacy), Associate Professor of Management and Economics Department of Pharmacy, Saint-Petersburg State Chemical and Pharmaceutical University

Russian Federation, 14, Prof. Popov Str., Saint-Petersburg, 197376

Zuriyadda B. Sakipova

Asfendiyarov Kazakh National Medical University

Email: sakipova.z@kaznmu.kz
ORCID iD: 0000-0003-4477-4051

Doctor of Sciences (Pharmacy), Professor, Dean of the School of Pharmacy, Asfendiyarov Kazakh National Medical University, Republic of Kazakhstan

Kazakhstan, Bld. 4, 88, Tole Bi Str., Almaty, 050000

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Supplementary files

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1. JATS XML
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2. Figure 1 – Scheme of UV rays exposure on human skin

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3. Figure 2 – Propagation of a light wave inside the skin

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4. Figure 3 – Transformation of thymine T and cytosine C when absorbing a UVB-wave photon

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5. Figure 4 – Skin exposure to UVA rays

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6. Figure 5 – Isomerization of urocaninic acid by a quantum of light under the conditions of exposure to UV rays

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7. Figure 6 – Principle of calculating SPF value

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8. Figure 7 – Methods for testing cellular bioprotection exposed to UV rays

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Copyright (c) 2023 Nemyatykh O.D., Terninko I.I., Sabitov A.S., Lyashko A.I., Sakipova Z.B.

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This work is licensed under a Creative Commons Attribution 4.0 International License.
 

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