Email this article Glycyrrhizic acid in the chronic vulvovaginitis and cervicitis treatment
- Authors: Ledina AV1, Prilepskaya VN1
-
Affiliations:
- ФГБУ Научный центр акушерства, гинекологии и перинатологии им. акад. В.И.Кулакова Минздрава РФ
- Issue: Vol 15, No 2 (2013)
- Pages: 58-60
- Section: Articles
- URL: https://ogarev-online.ru/2079-5831/article/view/28213
- ID: 28213
Cite item
Full Text
Abstract
Chronic vulvovaginitis and cervicitis are common pathological conditions in obstetrician-gynecologist practice. The main infectious agents, leading to their development are microorganisms and viruses. Causative treatment is carried out by means of the microscopic, microbiological or molecular biological survey methods. Due to changes in local immunity at chronic inflammation of the lower genital tract the use of immuno drugs (interferon and its inducers) is a necessary part of the pathogenetic therapy and is especially effective in treatment of vulvovaginitis associated with viral infection. Here, the data on the positive effect of glycyrrhizin acid complex treatment of chronic cervicitis and benign lesions cervix is presented.
Keywords
Full Text
##article.viewOnOriginalSite##About the authors
A V Ledina
ФГБУ Научный центр акушерства, гинекологии и перинатологии им. акад. В.И.Кулакова Минздрава РФ
Email: antoninaledina@yandex.ru
канд. мед. наук, врач поликлинического отд-ния
V N Prilepskaya
ФГБУ Научный центр акушерства, гинекологии и перинатологии им. акад. В.И.Кулакова Минздрава РФд-р мед. наук, проф., зам. дир., рук. научно-поликлинического отд-ния
References
- Кира Е.Ф., Муслимова С.З. Неспецифический вагинит и его влияние на репродуктивное здоровье женщины. Пробл. репрод. 2008; 5: 8–14.
- Mashburn J. Etiology, diagnosis, and management of vaginitis. J Midwifery Womens Health 2006; 51 (6): 423–30.
- Ekabua J.E et al. Adjuncts to case assessment of vaginal discharge syndrome in pregnant women. Asian Pac J Trop Med 2010; 3: 63–5.
- Hainer B.L, Gibson M.V. Vaginitis. Am Fam Physician 2011; 83 (7): 807–15.
- Swidsinski A et al. An adherent Gardnerella vaginalis biofilm persists on the vaginal epithelium after standard therapy with oral metronidazole. Am J Obstet Gynecol 2008; 198 (1): 97–106.
- Ferris M.J et al. Association of Atopobiumvaginae, a recently described metronidazole resistant anaerobe, with bacterial vaginosis. BMC Infect Dis 2004; 4: 5.
- Киселев В.И. и др. Онкобелок Е7 вируса папилломы человека – новый маркер ранних стадий канцерогенеза. Terra Medica 2011; 1: 35–9.
- Dunkelberger J.R, Song W.C. Role and mechanism of action of complement in regulating T cell immunity. Mol Immunol 2010; 47 (13): 2176–86.
- Stone S.F et al. Cytomegalovirus (CMV)-specific CD8+ T cells in individuals with HIV infection: correlation with protection from CMV disease. J Antimicrob Chemother 2006; 57 (4): 585–8.
- Gu X.B et al. Study on effects of kurarinol combined with glycyrrhizic acid on cellular immunity of patients with chronic hepatitis B. 2012; 26 (2): 108–10.
- Lin J.C et al. Inhibitory effects of some derivatives of glycyrrhizic acid against Epstein-Barr virus infection: structure - activity relationships. Antiviral Res 2008; 79 (1): 6–11.
- Wang J et al. Glycyrrhizic acid as the antiviral component of Glycyrrhiza uralensis Fisch. against coxsackie virus A16 and enterovirus 71 of hand foot and mouth disease. J Ethnopharmacol 2013; 147 (1): 114–21.
- Kukurtchu B. Activated glycyrrhizinic acid: significance against viral infections. Akush Ginekol (Sofiia) 2012; 51 (1). Suppl.: 46–7.
- Khan R et al. Glycyrrhizic acid suppresses the development of precancerous lesions via regulating the hyperproliferation, inflammation, angiogenesis and apoptosis in the colon of Wistar rats. PLoS One 2013; 8: 2.
- Ваганова С.Е. Комбинированное лечение доброкачественных заболеваний шейки матки. Акуш. и гинекол. 2010; 5: 116–20.
- Роговская С.И. и др. Повышение эффективности лечения заболеваний шейки матки: изучение опыта применения глицирризиновой кислоты. Рос. вестн. акуш. - гинекол. 2011; 5: 98–101.
Supplementary files
