Pharmacotherapy for diffuse alopecia
- Authors: Shperling N.V.1,2, Shperling M.I.3, Rudenko M.A.4, Chaplygin A.V.5
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Affiliations:
- University “Reaviz”
- Medical Center "Doctor+"
- Kirov Military Medical Academy
- International Medical Center "SOGAZ"
- Mechnikov North-Western State Medical University
- Issue: Vol 23, No 8 (2021)
- Pages: 621-625
- Section: Articles
- URL: https://ogarev-online.ru/2075-1753/article/view/97090
- DOI: https://doi.org/10.26442/20751753.2021.8.201126
- ID: 97090
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Abstract
Background. Diffuse alopecia (DA) is a pathological hair loss associated with damage to the hair follicle, usually associated with a trigger factor. An important role in the development of this condition is played by the violation of the cyclicity of the phases of the hair follicle – anagen, telogen and catagen. The basis of pathogenetic therapy for DA is the induction and prolongation of the anagen stage (including through inhibition of catagen). The use of medicines based on natural ingredients can get a positive effect on the course of the disease.
Aim. To evaluate the effectiveness of complex therapy with Selencin in the treatment of DA.
Materials and methods. The study was conducted on 80 patients with the proved diagnosis of DA (telogenic/anagenic). The treatment was carried out with Selencin in tablet form and external form (peptide lotion) for 2 months. The effectiveness of the drug was assessed 2 and 4 months after the start of treatment (immediately after the end of the course and 2 months later).
Results. The high clinical efficacy of the therapy has been shown in a significant reduction in hair loss, as well as restoration of their structure and increase in volume. Also, after 2 and 4 months from the start of treatment, there was a normalization of the dermatoscopic picture of the scalp and an improvement in the results of special tests (PULL test).
Conclusion. The use of a combination of drugs Selencin in the management of DA has a pronounced therapeutic effect. The drugs can be used as the primary treatment for this disease.
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##article.viewOnOriginalSite##About the authors
Natalia V. Shperling
University “Reaviz”; Medical Center "Doctor+"
Author for correspondence.
Email: shperling2@yandex.ru
D. Sci. (Med.)
Russian Federation, Saint Petersburg; Saint PetersburgMaksim I. Shperling
Kirov Military Medical Academy
Email: mersisaid@yandex.ru
Clinical Resident
Russian Federation, Saint PetersburgMarina A. Rudenko
International Medical Center "SOGAZ"
Email: rmacosm2@gmail.com
dermatovenerologist, trichologist
Russian Federation, Saint PetersburgAleksei V. Chaplygin
Mechnikov North-Western State Medical University
Email: av-chapl@yandex.ru
Cand. Sci. (Med.)
Russian Federation, Saint PetersburgReferences
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