The possibilities of modern nutraceuticals in the service fast track surgery ulcerogenic peritonitis

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Abstract

Objective. To study the effect of early enteral nutritional balanced mixtures containing glutamine in patients with ulcerative general fibrinous-purulent peritonitis in the docking compartment syndrome in the early postoperative period. Materials and methods. The study included 43 patients with perforated gastric ulcer, complicated by diffuse purulent peritonitis. All patients underwent an emergency surgical resection guide in the form of perforated ulcer. We used the technique of programmed (24-48 hours) rehabilitation of the abdominal cavity. In the main group, which includes 30 people, patients received in the structure of the above indicated basic treatment 500 ml of the product Intestamin. Results and its discussion. The use of a standard protocol of nutritional support, without a high content of glutamine resulted in the comparison group to almost two - fold increase in complications is an average of 38.5% and an increase in mortality in the group to 30.7%, while in the basic group the above figures were 20.0% and 16.6%, respectively. One of the significant reasons for the above difference was pronounced and the long - term cropped compartment syndrome in the control group, as well as the speed of its resolution on the background of Intestamin. Conclusions. Application Intestamin in the perioperative period in patients with peritonitis ulcerogenic justified by the possibility of full implementation of ERAS protocol, which in turn significantly affects the speed of the correction compartment syndrome and leads to a significant reduction in such important indicators as the number of complications, length of hospital stay, mortality.

About the authors

I. S Simutis

City Clinical Hospital №40

Email: simutis@mail.ru
канд. мед. наук, зав. отд-нием реанимации и интенсивной терапии ГБУЗ НО ГКБ №40 603083, Russian Federation, Nizhny Novgorod, ul. Geroia Iuriia Smirnova, d. 71

G. A Boyarinov

Nizhny Novgorod State Medical Academy of the Ministry of Health of the Russian Federation

д-р мед. наук, проф., зав. каф. анестезиологии и реаниматологии ФПКВ ГБОУ ВПО НижГМА Малиновская Ирина Александровна - гл.врач ГБУЗ НО ГКБ №40 603005, Russian Federation, Nizhny Novgorod, pl. Minina i Pozharskogo, d. 10/1

I. A Malinovskkaya

City Clinical Hospital №40

гл.врач ГБУЗ НО ГКБ №40 603083, Russian Federation, Nizhny Novgorod, ul. Geroia Iuriia Smirnova, d. 71

A. S Mukhin

Nizhny Novgorod State Medical Academy of the Ministry of Health of the Russian Federation

Email: prof.mukhin@mail.ru
д-р мед. наук, проф., зав. каф. хирургии ФПКВ ГБОУ ВПО НижГМА 603005, Russian Federation, Nizhny Novgorod, pl. Minina i Pozharskogo, d. 10/1

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