Minimizing Integration Interval in the Calculation of the Center of Gravity for an Elution Curve

Resumo

For the case of nonanalytical chromatography, elution curves have been simulated for the adsorbent layers different in relative lengths. By adjusting integration interval, the calculation errors are obtained for the center of gravity of an elution curve depending on the value of this interval, normalized with respect to its ratio to the time of the elution curve maximum. The obtained dependences make it possible to control the minimization of the integration interval and thereby to exclude from the calculated values the parts of the experimental curve that lead to additional errors in the calculation of moments owing to the drift and fluctuations of the baseline signal.