The phenomenon of atypical DNA comets

A. K. Zhanataev; E. A. Anisina; Z. V. Chayka; I. A. Miroshkina; A. D. Durnev

doi:10.1134/S1990519X17040113

The phenomenon of atypical DNA comets

Autores: Zhanataev A.K.¹, Anisina E.A.¹, Chayka Z.V.¹, Miroshkina I.A.¹, Durnev A.D.¹
Afiliações:
1. Zakusov Research Institute of Pharmacology
Edição: Volume 11, Nº 4 (2017)
Páginas: 286-292
Seção: Article
URL: https://ogarev-online.ru/1990-519X/article/view/212407
DOI: https://doi.org/10.1134/S1990519X17040113
ID: 212407

Citar

Texto integral

Acesso aberto
Acesso é fechado

Acesso está concedido
Acesso é fechado

Somente assinantes

Resumo
Sobre autores
Bibliografia
Arquivos suplementares
Estatísticas

Resumo

The phenomenon of atypical DNA comets observed in experiments using DNA-comet assay is described and illustrated. The current hypotheses explaining the nature of atypical DNA comets and our own take on the issue are considered. The practical importance of the registration of atypical DNA comets during the assessment of genotoxicity is discussed.

Palavras-chave

comet assay, atypical DNA comets, apoptosis, cytotoxicity, genotoxicity, oxidative stress, DNA damage