Prognostic relevance of the TNM classification 8th edition and new criteria of staging for retroperitoneal liposarcoma

封面

如何引用文章

全文:

详细

For the first time a section appeared for staging of non-organ retroperitoneal tumors in the UICC TNM classification 8th edition.

Aim. To assess the prognostic significance of the TNM classification eighth edition for the most common retroperitoneal tumors-liposarcoma.

Materials and methods. The distribution of patients by stages and survival in accordance with the TNM-8 classification were studied in 192 patients with retroperitoneal non-organ liposarcoma (RLPS).

Results. In the TNM-8 classification, only the degree of malignancy of the tumor has a prognostic value, and the T-category does not reflect the actual size of the RLPS and is considered T4 in 93%, which leads to inadequate staging. During the 15-year period, there were no cases with stages II and IIIA, and the survival rate was estimated only in patients with stages I and IIIB. A TNM classification with new values of the T-category was proposed, which demonstrated a more adequate distribution of patients by stages and the reliability of intergroup differences in the survival rate.

Conclusion. It is advisable to create a special TNM classification for RLPS, which makes up more than half of all retroperitoneal sarcomas.

作者简介

S. Nered

Blokhin National Medical Research Center of Oncology; Russian Medical Academy of Continuous Professional Education

Email: nered@mail.ru
SPIN 代码: 4588-3230

D. Sci. (Med.), Prof., Blokhin National Medical Research Centre of Oncology, Russian Medical Academy of Continuous Professional Education

俄罗斯联邦, Moscow

A. Volkov

Blokhin National Medical Research Center of Oncology

Email: 79164577128@yandex.ru
ORCID iD: 0000-0003-4412-2256
SPIN 代码: 3013-4392

Graduate Student, Blokhin National Medical Research Centre of Oncology

俄罗斯联邦, Moscow

N. Kozlov

Blokhin National Medical Research Center of Oncology

Email: newbox13@mail.ru
SPIN 代码: 1847-6530

Cand. Sci. (Med.), Blokhin National Medical Research Centre of Oncology

俄罗斯联邦, Moscow

I. Stilidi

Blokhin National Medical Research Center of Oncology; Russian Medical Academy of Continuous Professional Education

编辑信件的主要联系方式.
Email: istilidi@front.ru
SPIN 代码: 9622-7106

D. Sci. (Med.), Prof., Acad. RAS, Blokhin National Medical Research Centre of Oncology, Russian Medical Academy of Continuous Professional Education

俄罗斯联邦, Moscow

P. Archery

Blokhin National Medical Research Center of Oncology; Russian Medical Academy of Continuous Professional Education

Email: arhiri@mail.ru
SPIN 代码: 6880-4902

Cand. Sci. (Med.), Blokhin National Medical Research Centre of Oncology, Russian Medical Academy of Continuous Professional Education

俄罗斯联邦, Moscow

参考

  1. Каприн А.Д., Старинский В.В., Петрова Г.В. Состояние онкологической помощи населению России в 2017 году. М., 2018.
  2. [Kaprin A.D., Starinskiy V.V., Petrova G.V. The state of cancer care for the population of Russia in 2017. Moscow, 2018 (in Russian).]
  3. Liles JS, Tzeng CW, Short JJ et al. Retroperitoneal and intra-abdominal sarcoma. Curr Probl Surg 2009; 46 (6): 445–503. doi: 10.1067/j.cpsurg.2009.01.004
  4. Dalal KM, Kattan MW, Antonescu CR et al. Subtype specific prognostic nomogram for patients with primary liposarcoma of the retroperitoneum, extremity, or trunk. Ann Surg 2006; 244 (3): 381–91. doi: 10.1097/01.sla.0000234795.98607.00
  5. Fletcher CD, Bridge JA, Hogendoorn P, Mertens F. WHO Classification of Tumours of soft tissue and bone. 4th Ed. IARC. 2013; 33–44.
  6. Собин Л.Х., Господарович М.К., Виттекинд К. TNM: Классификация злокачественных опухолей. 2003; 6: 254.
  7. [Sobin L.Kh., Gospodarovich M.K., Vittekind K. TNM: Klassifikatsiya zlokachestvennykh opukholey. 2003; 6: 254 (in Russian).]
  8. Собин Л.Х., Господарович М.К., Виттекинд К. TNM: Классификация злокачественных опухолей. 2011; 7: 288.
  9. [Sobin L.Kh., Gospodarovich M.K., Vittekind K. TNM: Klassifikatsiya zlokachestvennykh opukholey. 2011; 7: 288 (in Russian).]
  10. Raut CP, Miceli R, Strauss DC et al. External validation of a multi-institutional retroperitoneal sarcoma nomogram. Cancer. 2016;122 (9):1417–24. doi: 10.1002/cncr.29931
  11. Неред С.Н., Стилиди И.С., Клименков А.А. и др. Клинико-морфологические особенности и результаты хирургического лечения забрюшинных неорганных липосарком. Вопр. онкологии. 2012; 58 (1): 94–100.
  12. [Nered S.N., Stilidi I.S., Klimenkov A.A. et al. Kliniko-morfologicheskiye osobennosti i rezul’taty khirurgicheskogo lecheniya zabryushinnykh neorgannykh liposarkom. Voprosy onkologii. 2012; 58 (1): 94–100 (in Russian).]
  13. Matthyssens LE, Creytens D, Ceelen WP. Retroperitoneal liposarcoma: current insights in diagnosis and treatment. Front Surg 2015; 2: 4. doi: 10.3389/fsurg.2015.00004
  14. Setsu N, Miyake M, Wakai S et al. Primary Retroperitoneal Myxoid Liposarcomas. Am J Surg Pathol 2016; 40 (9): 1286–90. doi: 10.1097/PAS.0000000000000657. PMID: 27158758; PMCID: PMC5029446.
  15. Liles JS, Tzeng CWD, Short JJ at al. Retroperitoneal and intra-abdominal sarcoma. Curr Probl Surg 2009; 46 (6): 445–503. doi: 10.1067/j.cpsurg.2009.01.004
  16. Bonvalot S, Rivoire M, Castaing M et al. Primary retroperitoneal sarcomas: a multivariate analysis of surgical factors associated with local control. J Clin Oncol 2009; 1; 27 (1): 31–7. doi: 10.1200/JCO.2008.18.0802. PMID: 19047280.
  17. Strauss DC, Hayes AJ, Thway K et al. Surgical management of primary retroperitoneal sarcoma. Br J Surg 2010; 97 (5): 698–706. doi: 10.1002/bjs.6994
  18. Ardoino I, Miceli R, Berselli M et al. Histology-specific nomogram for primary retroperitoneal soft tissue sarcoma. Cancer 2010; 116 (10): 2429–36. doi: 10.1002/cncr.25057. PMID: 20209615.
  19. Gronchi A, Miceli R, Shurell E et al. Outcome prediction in primary resected retroperitoneal soft tissue sarcoma: histology-specific overall survival and disease-free survival nomograms built on major sarcoma center data sets. J Clin Oncol 2013; 31 (13): 1649–55. doi: 10.1200/JCO.2012.44.3747
  20. Abbott AM, Habermann EB, Parsons HM et al. Prognosis for primary retroperitoneal sarcoma survivors: a conditional survival analysis. Cancer 2012; 118 (13): 3321–29. doi: 10.1002/cncr.26665
  21. Brierley JD, Gospodarowicz MK, Wittekind Ch. TNM classification of malignant tumours. 8th ed New York: Wiley-Blackwell, 2017.
  22. Волков А.Ю., Неред С.Н., Любченко Л.Н. Забрюшинные неорганные липосаркомы: современный взгляд на проблему. Сиб. онкол. журнал. 2019; 18 (5): 86–96. doi: 10.21294/1814-4861-2019-18-5-86-96
  23. [Volkov A.Yu., Nered S.N., Lyubchenko L.N. Zabryushinnyye neorgannyye liposarkomy: sovremennyy vzglyad na problemu. Sib. onkologicheskiy zhurn. 2019; 18 (5): 86–96. doi: 10.21294/1814-4861-2019-18-5-86-96 (in Russian).]
  24. Antonescu CR, Tschernyavsky SJ, Decuseara R et al. Prognostic impact of P53 status, TLS-CHOP fusion transcript structure, and histological grade in myxoid liposarcoma: a molecular and clinicopathologic study of 82 cases. Clin Cancer Res 2001; 7 (12): 3977–87.
  25. Geethamani V, Savithri R, Suguna BV, Niveditha SR. Cytomorphology of dedifferentiated liposarcoma of the subcutis of the upper back with axillary lymph node metastasis: a case report. Acta Cytol 2010; 54: 333–6.
  26. Gritli S, Khamassi K, Lachkhem A et al. Head and neck liposarcomas: a 32 years experience. Auris Nasus Larynx 2010; 37: 347–51.
  27. Schofer MD, Abu-Safieh MY, Paletta J et al. Liposarcoma of the forearm in a man with type 1 neurofibromatosis: a case report. J Med Case Reports 2009; 3: 7071.
  28. Correia de Sá IB, Carvalho J, Silva R et al. Liposarcoma with lymph node spread: a case presentation and a systematic review of the literature. Euro Surg 2015; 47: 94–100.

补充文件

附件文件
动作
1. JATS XML

版权所有 © Consilium Medicum, 2020

Creative Commons License
此作品已接受知识共享署名-非商业性使用 4.0国际许可协议的许可。
 


Согласие на обработку персональных данных

 

Используя сайт https://journals.rcsi.science, я (далее – «Пользователь» или «Субъект персональных данных») даю согласие на обработку персональных данных на этом сайте (текст Согласия) и на обработку персональных данных с помощью сервиса «Яндекс.Метрика» (текст Согласия).