CHRONIC PERIODONTITIS CO-MORBIDWITHKNEEJOINT OSTEOARTHRITIS:INDUCTION ANDPROLONGATION OF REMISSION, OUTCOMES OF THE TREATMENT

In the present study the criteria of evidence-based medicine were applied for the estimation of the efficacy of two methods designed to induce clinical remission and its prolongation in the patients presenting with chronic periodontitis and concomitant knee joint osteoarthritis. Monotherapy with the use of the arthrofoon preparation containing ultralow doses of antibodies against tumour necrosis factor-alpha, the principal anti-inflammatory cytokine, was carried out during a period of up to 12 months. The data obtained were compared with the results of traditional "upon request" therapy in the patients who had refused to undergo treatment with arthrofoon and suffered exacerbation of clinical symptoms. The evaluation of the outcomes of both therapeutic modalities in terms of evidence-based medicine and revealed high efficacy of arthrofoon monotherapy for the treatment of combined stomatological and arthrological pathology.

periodontitis, osteoarthritis, arthrofoon