Methods for obtaining solid dispersions of drugs and their properties
- Авторы: Khalikov S.S.1, Lokshin B.V.1, Ilyin M.M.1, Varlamova A.I.2, Musaev M.B.2, Arhipov I.A.2
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Учреждения:
- A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences
- All-Russian Research Institute of Fundamental and Applied Parasitology of Animals and Plants – Branch of the Federal State Budgetary Scientific Institution “Federal Scientific Center – K. I. Skryabin and Ya. R. Kovalenko All-Russian Scientific Research Institute of Experimental Veterenary Medicine”, Russian Academy of Sciences
- Выпуск: Том 68, № 10 (2019)
- Страницы: 1924-1932
- Раздел: Full Articles
- URL: https://ogarev-online.ru/1066-5285/article/view/243509
- DOI: https://doi.org/10.1007/s11172-019-2648-3
- ID: 243509
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Аннотация
The possibility of improving the solubility of drugs by obtaining solid dispersions (SDs) with polymers is demonstrated. The solubility of these SDs is dependent both on the nature of drug and polymer and on the conditions of their preparation. IR spectroscopy of the obtained SDs and the analysis of results found in literature indicate that inclusion complexes are formed within them.
Об авторах
S. Khalikov
A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences
Автор, ответственный за переписку.
Email: salavatkhalikov@mail.ru
Россия, 28 ul. Vavilova, Moscow, 119991
B. Lokshin
A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences
Email: salavatkhalikov@mail.ru
Россия, 28 ul. Vavilova, Moscow, 119991
M. Ilyin
A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences
Email: salavatkhalikov@mail.ru
Россия, 28 ul. Vavilova, Moscow, 119991
A. Varlamova
All-Russian Research Institute of Fundamental and Applied Parasitology of Animals and Plants – Branch of the Federal State Budgetary Scientific Institution “Federal Scientific Center – K. I. Skryabin and Ya. R. Kovalenko All-Russian Scientific Research Institute of Experimental Veterenary Medicine”, Russian Academy of Sciences
Email: salavatkhalikov@mail.ru
Россия, 28 ul. B. Cheremushkinskaya, Moscow, 117218
M. Musaev
All-Russian Research Institute of Fundamental and Applied Parasitology of Animals and Plants – Branch of the Federal State Budgetary Scientific Institution “Federal Scientific Center – K. I. Skryabin and Ya. R. Kovalenko All-Russian Scientific Research Institute of Experimental Veterenary Medicine”, Russian Academy of Sciences
Email: salavatkhalikov@mail.ru
Россия, 28 ul. B. Cheremushkinskaya, Moscow, 117218
I. Arhipov
All-Russian Research Institute of Fundamental and Applied Parasitology of Animals and Plants – Branch of the Federal State Budgetary Scientific Institution “Federal Scientific Center – K. I. Skryabin and Ya. R. Kovalenko All-Russian Scientific Research Institute of Experimental Veterenary Medicine”, Russian Academy of Sciences
Email: salavatkhalikov@mail.ru
Россия, 28 ul. B. Cheremushkinskaya, Moscow, 117218
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