Polysiloxane based on hydroxyl-containing monomer. Preparation, properties and biomedical application

T. S. Lyubova; N. S. Zakharycheva; E. A. Zakharychev; S. A. Lermontova; E. Yu. Ladilina; L. G. Klapshina

doi:10.1007/s11172-019-2522-3

Polysiloxane based on hydroxyl-containing monomer. Preparation, properties and biomedical application

Autores: Lyubova T.S.¹, Zakharycheva N.S.², Zakharychev E.A.², Lermontova S.A.¹, Ladilina E.Y.¹, Klapshina L.G.¹
Afiliações:
1. Razuvaev Institute of Organometallic Chemistry, Russian Academy of Sciences
2. Lobachevsky State University of Nizhny Novgorod
Edição: Volume 68, Nº 5 (2019)
Páginas: 1075-1080
Seção: Full Article
URL: https://ogarev-online.ru/1066-5285/article/view/243383
DOI: https://doi.org/10.1007/s11172-019-2522-3
ID: 243383

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A method for synthesis of hyperbranched polysiloxane based on N-methyl-N-(2,3,4,5,6-pentahydroxyhexyl)-N’-(3-triethoxysilylpropyl)urea is proposed. In water, the polymer forms nanoparticles capable of holding low soluble luminophores (tetracyanotetraarylporphyrazines) due to non-covalent interaction. Intensively luminescent stable aqueous suspensions based on non-toxic siloxane nanoparticles can be used in bioimaging.