Enviar artigo por via de e-mail Acyl derivatives of ivermectin 5-oxime with antifungal activity
- Autores: Chernoburova E.I.1, Shchetinina M.A.1, Dzhafarov M.K.1, Krylov V.B.1, Zavarzin I.V.1
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Afiliações:
- N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences
- Edição: Volume 68, Nº 2 (2019)
- Páginas: 438-444
- Seção: Full Articles
- URL: https://ogarev-online.ru/1066-5285/article/view/243266
- DOI: https://doi.org/10.1007/s11172-019-2405-7
- ID: 243266
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Resumo
Acylation of ivermectin 5-oxime was first studied. Procedures for selective acylation of ivermectin 5-oxime either selectively at 5-oxime group or at both 5-oxime group and 4″-hydroxy group to give, respectively, mono- and diacyl derivatives were developed. The synthesized compounds exhibit antifungal activity.
Sobre autores
E. Chernoburova
N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences
Email: zavi@ioc.ac.ru
Rússia, 47 Leninsky prosp., Moscow, 119991
M. Shchetinina
N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences
Email: zavi@ioc.ac.ru
Rússia, 47 Leninsky prosp., Moscow, 119991
M. Dzhafarov
N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences
Email: zavi@ioc.ac.ru
Rússia, 47 Leninsky prosp., Moscow, 119991
V. Krylov
N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences
Email: zavi@ioc.ac.ru
Rússia, 47 Leninsky prosp., Moscow, 119991
I. Zavarzin
N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences
Autor responsável pela correspondência
Email: zavi@ioc.ac.ru
Rússia, 47 Leninsky prosp., Moscow, 119991
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