Enviar artigo por via de e-mail 2,6-Disubstituted 4-azidopyrimidines: synthesis, kinetic and thermodynamic studies of azide-tetrazole rearrangement by NMR spectroscopy
- Autores: Pleshkova N.V.1, Nikolaenkova E.B.1, Krivopalov V.P.1, Mamatyuk V.I.1,2
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Afiliações:
- N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry of Siberian Branch, Russian Academy of Sciences
- Novosibirsk State University (National Research University)
- Edição: Volume 66, Nº 11 (2017)
- Páginas: 2095-2102
- Seção: Full Article
- URL: https://ogarev-online.ru/1066-5285/article/view/241562
- DOI: https://doi.org/10.1007/s11172-017-1986-2
- ID: 241562
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Resumo
Thermodynamic and kinetic parameters of the tautomeric tetrazole-azide rearrangement for a series of 2,6-disubstituted 4-azidopyrimidines are determined by NOESY/EXSY and DNMR: ΔH = 15—28 kJ mol–1; ΔS = 47—65 J mol–1 К–1; Еa = 93—117 kJ mol–1; lgA = 15.1—18.9. They are dependent on electronic properties of the substituents and the polarity of solvent.
Sobre autores
N. Pleshkova
N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry of Siberian Branch, Russian Academy of Sciences
Autor responsável pela correspondência
Email: Nadia789@nioch.nsc.ru
Rússia, 9 prosp. Lavrentieva, Novosibirsk, 630090
E. Nikolaenkova
N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry of Siberian Branch, Russian Academy of Sciences
Email: Nadia789@nioch.nsc.ru
Rússia, 9 prosp. Lavrentieva, Novosibirsk, 630090
V. Krivopalov
N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry of Siberian Branch, Russian Academy of Sciences
Email: Nadia789@nioch.nsc.ru
Rússia, 9 prosp. Lavrentieva, Novosibirsk, 630090
V. Mamatyuk
N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry of Siberian Branch, Russian Academy of Sciences; Novosibirsk State University (National Research University)
Email: Nadia789@nioch.nsc.ru
Rússia, 9 prosp. Lavrentieva, Novosibirsk, 630090; 2 ul. Pirogova, Novosibirsk, 630090
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