Enviar artigo por via de e-mail Synthesis and cytotoxic activity of usnic acid cyanoethyl derivatives
- Autores: Rakhmanova M.E.1,2, Luzina O.A.1, Pokrovskii M.A.2, Pokrovskii A.G.2, Salakhutdinov N.F.1,2
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Afiliações:
- N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences
- Novosibirsk State University
- Edição: Volume 65, Nº 2 (2016)
- Páginas: 566-569
- Seção: Full Articles
- URL: https://ogarev-online.ru/1066-5285/article/view/237329
- DOI: https://doi.org/10.1007/s11172-016-1338-7
- ID: 237329
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Resumo
Cyanoethyl derivatives of usnic acid (natural lichen metabolite) were prepared. The reaction proceeded as a C-alkylation process via addition of two acrylonitrile molecules. Cytotoxic effect of the synthesized derivatives on the blood tumor cell lines was studied.
Sobre autores
M. Rakhmanova
N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences; Novosibirsk State University
Email: luzina@nioch.nsc.ru
Rússia, 9 prosp. Akad. Lavrent’eva, Novosibirsk, 630090; 2 ul. Pirogova, Novosibirsk, 630090
O. Luzina
N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences
Autor responsável pela correspondência
Email: luzina@nioch.nsc.ru
Rússia, 9 prosp. Akad. Lavrent’eva, Novosibirsk, 630090
M. Pokrovskii
Novosibirsk State University
Email: luzina@nioch.nsc.ru
Rússia, 2 ul. Pirogova, Novosibirsk, 630090
A. Pokrovskii
Novosibirsk State University
Email: luzina@nioch.nsc.ru
Rússia, 2 ul. Pirogova, Novosibirsk, 630090
N. Salakhutdinov
N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences; Novosibirsk State University
Email: luzina@nioch.nsc.ru
Rússia, 9 prosp. Akad. Lavrent’eva, Novosibirsk, 630090; 2 ul. Pirogova, Novosibirsk, 630090
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