Effect of Shock Waves Generated by Pulsed Electric Discharges in Water on Yeast Cells and Virus Particles
- Авторлар: Girdyuk A.E.1, Gorshkov A.N.2, Egorov V.V.2,3, Kolikov V.A.1, Snetov V.N.1, Shneerson G.A.4
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Мекемелер:
- Institute of Electrophysics and Electric Power
- Research Institute of Influenza
- St. Petersburg Nuclear Physics Institute
- St. Petersburg Technical University
- Шығарылым: Том 63, № 2 (2018)
- Беттер: 285-290
- Бөлім: Biomedical Physics
- URL: https://ogarev-online.ru/1063-7842/article/view/200802
- DOI: https://doi.org/10.1134/S1063784218020159
- ID: 200802
Дәйексөз келтіру
Аннотация
The aim of this study is to determine the optimal parameters of the electric pulses and shock waves generated by them for the soft destruction of the virus and yeast envelopes with no changes in the structure of antigenic surface albumin and in the cell morphology in order to use them to produce antivirus vaccines and in biotechnology. The pulse electric discharges in water have been studied for different values of amplitude, pulse duration and the rate of the rise in the current. A mathematical model has been developed to estimate the optimal parameters of pulsed electric charges and shock waves for the complete destruction of the yeast cell envelopes and virus particles at a minimum of pulses.
Авторлар туралы
A. Girdyuk
Institute of Electrophysics and Electric Power
Email: kolikov1@yandex.ru
Ресей, St. Petersburg, 191186
A. Gorshkov
Research Institute of Influenza
Email: kolikov1@yandex.ru
Ресей, St. Petersburg, 197376
V. Egorov
Research Institute of Influenza; St. Petersburg Nuclear Physics Institute
Email: kolikov1@yandex.ru
Ресей, St. Petersburg, 197376; Gatchina, 188300
V. Kolikov
Institute of Electrophysics and Electric Power
Хат алмасуға жауапты Автор.
Email: kolikov1@yandex.ru
Ресей, St. Petersburg, 191186
V. Snetov
Institute of Electrophysics and Electric Power
Email: kolikov1@yandex.ru
Ресей, St. Petersburg, 191186
G. Shneerson
St. Petersburg Technical University
Email: kolikov1@yandex.ru
Ресей, St. Petersburg, 195251
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