RECEPTOR AND PHAGOCYTIC ACTIVITY OF NEUTROPHILS IN CHRONIC DISEASES OF THE UPPER GASTROINTESTINAL TRACT IN CHILDREN, ASSOCIATED WITH HELICOBACTER PYLORI, AND FUNGI OF THE GENUS CANDIDA
- 作者: Agafonova E.V.1, Velinsky T.A.1
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隶属关系:
- Kazan state medical University FBUN KNIIM Central research Institute of Rospotrebnadzor
- 期: 卷 20, 编号 2 (2017)
- 页面: 241-243
- 栏目: Articles
- URL: https://ogarev-online.ru/1028-7221/article/view/119767
- ID: 119767
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In children with chronic diseases of the upper gastrointestinal tract associated with Helicobacter pylori, and Helicobacter pylori association with fungi of the genus Candida, study of the receptor apparatus (adhesion, to the components of complement-CR 3, Fc fragment of Ig G and activation markers) and phagocytic activity of neutrophils. The identified differentiated characteristics of the phagocytic activity and immunophenotype in Helicobacter pylori infection and association with fungi of the genus Candida. Mannoproteins circulating antigen of Candida albicans affects the immunophenotype of neutrophils, inducing the expression of proapoptotic and reducing the expression of adhesion receptors and cytolysis.
作者简介
E. Agafonova
Kazan state medical University FBUN KNIIM Central research Institute of Rospotrebnadzor
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Email: noemail@neicon.ru
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T. Velinsky
Kazan state medical University FBUN KNIIM Central research Institute of Rospotrebnadzor
Email: noemail@neicon.ru
俄罗斯联邦
参考
- Маланичева Т. Г., Зиатдинова Н. В., Файзуллина Р. А., Нарыков Р. Х. Иммунологические нарушения у детей с хронической гастродуоденальной патологией. Практическая медицина 2011, 5,16-19.
- Moraes-Vasconcelos D., Orii N. M., Romano C. C. et al. Characterization of the cellular immune function of patients with chronic mucocutaneous candidiasis. Clin. Exp. Immunol. 2008. 2(suppl.), 247-253.
- Нестерова И.В., Швыдчеко И. Н., Роменская В. А. и др. Нейтрофильные гранулоциты - ключевые клетки иммунной системы. Аллергология и иммунология 2008, 4, 432-435.
- Wormley F. L., Chaiban].R., Fidel P. L. Cell adhesion molecule and lymphocyte activation marker expression during experimental vaginal candidiasis. Infect. Immun.2001,8(suppl.),5072-5079.
- Han Y., Ulrich M. A., Cutler].E. Candida albicans mannan extract-protein conjugates induce immune response against experimental candidiasis. J. Infect. Dis. 2009, 6(suppl.), 1477-1484.
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