Enviar artigo por via de e-mail Anxious and melancholic depression are followed by differently directed serum albumin conformation
- Autores: Uzbekov M.G.1, Smolina N.V.1, Syrejshchikova T.I.1, Maximova N.M.1, Shikhov S.N.1, Dobretsov G.E.1, Brilliantova V.V.1, Krjukov V.V.1
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Afiliações:
- Moscow Research Institute of Psychiatry
- Edição: Volume 41, Nº 1 (2024)
- Páginas: 14-18
- Seção: Clinical Neurochemistry
- URL: https://ogarev-online.ru/1027-8133/article/view/259331
- DOI: https://doi.org/10.31857/S1027813324010022
- EDN: https://elibrary.ru/GZHVIJ
- ID: 259331
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Resumo
The aim of the study was investigation of the peculiarities of the conformational changes of serum albumin in patients with anxious and melancholic depression. Albumin conformation was measured by the method of the subnanosecond laser time resolved fluorescence spectroscopy. Anxious depression was followed with the significant decrease of the values of the three amplitudes on the serum albumin in comparison with controls. In the melancholic depression the values of all three amplitudes on serum albumin molecules were significantly elevated in comparison with controls. These results are clearly indicated that anxious and melancholic depression are followed by differently directed changes in serum albumin conformation.
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Sobre autores
M. Uzbekov
Moscow Research Institute of Psychiatry
Autor responsável pela correspondência
Email: uzbekovmg@gmail.com
Rússia, Moscow
N. Smolina
Moscow Research Institute of Psychiatry
Email: uzbekovmg@gmail.com
Rússia, Moscow
T. Syrejshchikova
Moscow Research Institute of Psychiatry
Email: uzbekovmg@gmail.com
Rússia, Moscow
N. Maximova
Moscow Research Institute of Psychiatry
Email: uzbekovmg@gmail.com
Rússia, Moscow
S. Shikhov
Moscow Research Institute of Psychiatry
Email: uzbekovmg@gmail.com
Rússia, Moscow
G. Dobretsov
Moscow Research Institute of Psychiatry
Email: uzbekovmg@gmail.com
Rússia, Moscow
V. Brilliantova
Moscow Research Institute of Psychiatry
Email: uzbekovmg@gmail.com
Rússia, Moscow
V. Krjukov
Moscow Research Institute of Psychiatry
Email: uzbekovmg@gmail.com
Rússia, Moscow
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