Dinitrodibenzo [B,D]Oxepin-7(6h)-One Antiproliferative Activity Against Hepg2 Cells

Qiang Li; ShaoPing Sun; XianFeng Gong

doi:10.1007/s11094-019-02050-8

Dinitrodibenzo [B,D]Oxepin-7(6h)-One Antiproliferative Activity Against Hepg2 Cells

作者: Li Q.¹, Sun S.¹, Gong X.¹
隶属关系:
1. Heilongjiang University, School of Chemistry and Materials Science
期: 卷 53, 编号 7 (2019)
页面: 624-627
栏目: Article
URL: https://ogarev-online.ru/0091-150X/article/view/245906
DOI: https://doi.org/10.1007/s11094-019-02050-8
ID: 245906

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详细

The cytotoxic activity of twenty three new biphenyl compounds was investigated, and the IC₅₀ value of 1,2-dinitrodibenzo [b,d]oxepin-7(6H)-one (DNDBO) was found to be the lowest among these compounds. The underlying mechanism of DNDBO-induced cell death was explored.