Development and Validation of a Quantitative Determination Technique for Phenibut in Microcapsules
- 作者: Polkovnikova Y.A.1, Koryanova K.N.2, Slivkin A.I.1, Tul’skaya U.A.1, Senchenko S.P.2
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隶属关系:
- Voronezh State University
- Pyatigorsk Medico-Pharmaceutical Institute, Branch of Volgograd State Medical University
- 期: 卷 52, 编号 9 (2018)
- 页面: 803-807
- 栏目: Article
- URL: https://ogarev-online.ru/0091-150X/article/view/245477
- DOI: https://doi.org/10.1007/s11094-018-1904-4
- ID: 245477
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详细
A capillary electrophoresis technique for quantitative determination of phenibut in microcapsules was developed and validated. Rather high efficiencies (~200,000 theoretical plates) and the required resolution (Rs ≥ 1.5) were attained using sodium tetraborate decahydrate solution (10 mM) at pH 9.2 as the supporting electrolyte. Validation of the technique showed that it was specific and complied with requirements of the SP XIIIth Ed. with respect to analytical range and linearity.
作者简介
Yu. Polkovnikova
Voronezh State University
编辑信件的主要联系方式.
Email: juli-polk@mail.ru
俄罗斯联邦, Studencheskaya St., Voronezh, 394006
K. Koryanova
Pyatigorsk Medico-Pharmaceutical Institute, Branch of Volgograd State Medical University
Email: juli-polk@mail.ru
俄罗斯联邦, 11 Kalinina Prosp., Pyatigorsk, Stavropol’skii Krai, 357532
A. Slivkin
Voronezh State University
Email: juli-polk@mail.ru
俄罗斯联邦, Studencheskaya St., Voronezh, 394006
U. Tul’skaya
Voronezh State University
Email: juli-polk@mail.ru
俄罗斯联邦, Studencheskaya St., Voronezh, 394006
S. Senchenko
Pyatigorsk Medico-Pharmaceutical Institute, Branch of Volgograd State Medical University
Email: juli-polk@mail.ru
俄罗斯联邦, 11 Kalinina Prosp., Pyatigorsk, Stavropol’skii Krai, 357532
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